Last run I did with 8m solexa 60bp reads on normal took just under 7 hours with 67+GB of ram and once you run out of ram your computer has to use the hard drive which is 1000 times slower. I think its safe to say with your assembly and hardware you would be looking at months (?years possibly?) According to this site http://www.terryscomputertips.com/computers/speed-of-virtual-memory-versus-ram/ it is a difference of* *1,300,000 x slower On Mon, Dec 20, 2010 at 1:59 AM, Ganga Jeena <ganga.jeena@xxxxxxxxx> wrote: > I am trying to do assembly of 8 million reads with mira > Configuration of system is as follows: > 512 GB RAM > 8 hexa-core processors > > miramem gives me a memory estimate of 66.6 GB. > How to get the time-estimate for assembly of data on my system. > Regards, > Ganga Jeena > > > >