On 06/04/11 22:31, John Nash wrote:
Dear all, If you think that this is off-topic, please advise and I will shut up. On 2011-04-06, at 4:08 PM, Robin Kramer wrote:Generally I prefer the way they teach in CS, where you implement the algorithm. IE actually program a dynamic alignment algorithm. If you can do that then picking up a new alignment algorithm, isn't too difficult. I find so many people are high centered on a technology because they only know the switches for that particular black box, so they resist even keeping up to date on the latest versions of their favorite software. Sincerely yours, RobinIt depends on how you want to look at it. Many of us are doing this because we are trying to solve biological problems. We don't really care how (as in mechanistically) it works, only that it is accurate in answering my biological question. John
Just as a note, a piece of software is never intended to solve a "biological" question but rather a mathematical simplification of the problem through a specific method. Therefore, it is crucial to understand the mathematical simplification as well as the key steps of the method in order to determine if it applies to your specific "biological" question.
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