[mira_talk] Re: 32-bit version for mira 3.2.1?
- From: Lionel Guy <guy.lionel@xxxxxxxxx>
- To: mira_talk@xxxxxxxxxxxxx
- Date: Wed, 6 Apr 2011 21:38:42 +0200
There is a very thorough and very good exercise devised by Bill Pearson (the
one who made FASTA) on the website of the Workshop for Molecular Evolution. It
shows the different programs and the use of different matrices, and in general
how to relate e-values to homology:
http://workshop.molecularevolution.org/resources/activities/fasta_blast_activity
There is also the accompanying presentation (pretty dense, but very precise):
http://www.molecularevolution.org/molevolfiles/presentations/pearson_wcg11_11a.pdf
Lionel
On 6 Apr 2011, at 21:24 , Robin Kramer wrote:
> Not quite blast for dummies, but there is a chapter in "Bioinformatics for
> Dummies" on BLAST.
>
> http://books.google.com/books?id=4Tw0aZBnBLEC&pg=PA201&lpg=PA201&dq=blast+for+dummies&source=bl&ots=uKqjK6w6wu&sig=Q4SQ7XvjLsILgwC0WmpWFdUJw70&hl=en&ei=wLycTfbmI4r0tgO54_CLBA&sa=X&oi=book_result&ct=result&resnum=4&ved=0CCkQ6AEwAw#v=onepage&q=blast%20for%20dummies&f=false
>
> I love that "The parameters for blast are quite optimal, there is little
> reason to change these, unless of course...".
>
> Sincerely yours,
>
> Robin
>
> On Wed, Apr 6, 2011 at 12:58 PM, Bastien Chevreux <bach@xxxxxxxxxxxx> wrote:
> On Wednesday 06 April 2011 16:55:57 Robin Kramer wrote:
> > I don't know why I was thinking it would be using the text book, "Blast for
> > dummies".
> Some of the "for dummies" books are actually excellent introductions into
> topics when people have absolutely no plan (others are crap, granted).
> And incidentally, just a couple of weeks ago I wished a "for dummies" book
> existed on BLAST. You don't want to know how some people simply misuse that
> tool and then wonder nothing substantial comes out of wet-lab follow-up
> experiments ... ;-)
> B.
>
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