The story of panic attacks:- 1. Before David Clark?s work, the prevailing orthodoxy was that panic attacks are primarily ?biological? rather than ?psychological? because:- a) they can be induced biologically (using sodium lactate infusions, for example). b) apparent heritability: more than half of sufferers have relatives with some anxiety disorder or alcoholism; and if one of two identical twins has panic attacks then 31 % of co-twins has them whereas if one of two fraternal twins has them none of the co-twins are so afflicted. c) specific brain functions appear to be involved with sufferers showing abnormalities in brain chemistry and abnormal blood flow and oxygen use in the relevant parts of their brain. d) drugs can dampen and even eliminate panic attacks. 2. Clark turned this on its head; he argued ? what if an apparent symptom of a panic attack (feelings of morbid dread, of having a heart attack, of being about to faint etc. ? in general terms, a catastrophic interpretation of bodily sensations) was actually their root cause? 3. This theory fits the biological findings well: a) sodium lactate makes the heart race creating an initial bodily sensation that it is then interpreted catastrophically. b) panic may be partially heritable because having a particularly noticeable bodily sensation (e.g. palpitations) is heritable not because panicking is itself heritable. c) specific brain areas are activated not as a cause but as a symptom of panic. d) drugs relieve panic by quelling the unpleasant bodily sensations that provoke a catastrophic reaction. 4. Clark and a fellow researcher, Paul Salkovskis, did further experiments that showed: a) persons with anxiety disorders are quicker to see the catastrophic ending of a sentence than ?normals? (showing they have a catastrophic way of interpreting). b) persons prone to panic attacks, but not ?normals? or recovered panic patients, can have panics induced by reading aloud word pairs such as ?breathlessness-suffocation?. 5. Clark also helped develop a new cognitive therapy for panic attacks that appeared highly effective ? more effective and less dangerous than drug treatment. It involves explaining the physiological mechanics of a panic attack ? for example, that though a person might feel about to faint this could only in fact happen if their blood pressure dropped but during an attack blood pressure shoots up; the feeling of faintness is due to a small drop of oxygen to the brain caused by blood being diverted to the muscles away from the brain as part of a ?fight-or-flight- response to perceived danger. 6. The success of this therapy nevertheless does not show the cause of panic attacks is cognitive. Clark?s simple and devastating differential prediction is as follows. Panic-patients were given an infusion of lactate and?Oh god, I?ve forgotten it again. Donal ___________________________________________________________ Switch an email account to Yahoo! Mail, you could win FIFA World Cup tickets. http://uk.mail.yahoo.com ------------------------------------------------------------------ To change your Lit-Ideas settings (subscribe/unsub, vacation on/off, digest on/off), visit www.andreas.com/faq-lit-ideas.html