[ SHOWGSD-L ] Re: Von Willebrand's disease

  • From: Kate Syssoloff <rockannand@xxxxxxx>
  • To: managsd@xxxxxxxxx
  • Date: Wed, 14 Nov 2012 23:11:08 -0700 (MST)

Wow, sorry to hear VWD is still around.  In 1979, I had an import male (Hal), 
that was tested affected.  It's been many years since I studied the disease.  
In my male's case, he inherited it from his mother (most do).  They call it sex 
linked., and males suffer from it more than females.  Many puppies never 
survive because they bleed from their umbilical, my guy's numbers were not as 
low as they could have been and I guess that helped him.  He was not very old 
when he died, 5 1/2 ... just the slightest bruises sent him into the ER.  In 
those few years, Hal had received 3 blood transfusions to save his life.

Kate
Rockannand 

----- Original Message -----
From: "Catherine Morton" <managsd@xxxxxxxxx>
To: Showgsd-l@xxxxxxxxxxxxx
Sent: Wednesday, November 14, 2012 6:03:33 PM
Subject: [ SHOWGSD-L ] Von Willebrand's disease

Hello, 
Question for the genetic literates in the crowd.
My friends have a young bitch that bloated, and during surgery found out she 
has Von Willebrands. 
I know there is a genetic component in this disease, as well as a genetic test 
to determine affected/carrier/clear status, as well as a test we use at work to 
determine if they are affected, so I know where to go that way if I want to 
test a dog.
My question is, what is the inheritance of this disease? Is it simple recessive 
or is it like mega where there are modes of penetrance that makes it more 
complicated?
I havent found a website that breaks it down for our breed.
I'm just curious, of course I have to know details lol.
Catherine Morton LVT
 

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POST is Copyrighted 2012.  All material remains the property of the original 
author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind 
are permitted without prior permission of the original author AND of the 
Showgsd-l Management. ALL RIGHTS RESERVED. 

Each Author is responsible for the content of his/her post.  This group and its 
administrators are not responsible for the comments or opinions expressed in 
any post.

ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY 
MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS 
PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY 
FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE 
PROSECUTED. 

For assistance, please contact the List Management at admin@xxxxxxxxxxx

VISIT OUR WEBSITE - http://showgsd.org  
SUBSCRIPTION:http://showgsd.org/mail.html
NATIONAL BLOG - http://gsdnational.blogspot.com/
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