On Montag 22 November 2010 Laurent MANCHON wrote: > Genome assembly is a big problem moreover when you have more and more > reads, i just got a genome of 400 Mb finished and I can tell i was > monitoring the RAM of the server for many weeks... > I have used the latest ABYSS with 320 millions of reads. > [...] > I have tested Mira for Paired-end assembly and with million of reads > mira is a beast that consumes a lot of RAM ...and has a bad memory > footprint. Yeah, there are a couple of things MIRA is not good at ... working with >20 to 40 million reads is one of them. I think the future of (de-novo) sequencing will not stay with short reads. Therefore I'll work on improving behaviour with ultra-high read numbers gradually, but put my priorities on a couple of other things. B. -- You have received this mail because you are subscribed to the mira_talk mailing list. For information on how to subscribe or unsubscribe, please visit http://www.chevreux.org/mira_mailinglists.html