For bioinformatics I suggest dual or quado AMD Opteron(tm) 6376 CPUs, they each have 16 cores. MIRA doesn't speed up much with the more cores you use, I think the plateau was at 8 or 16, I remember someone discussing this. You also need more RAM, 256 GB will soon be a bare minimum. I would be very surprised if MIRA was CUDA enabled.In fact, very little things are. I only know of a few bayesian phylogenetic analysis methods. On Sat, May 31, 2014 at 4:23 PM, Chayan Roy <chayan.roy93@xxxxxxxxx> wrote: > Hi All, > > In recent time I have assembled few genomes. Currently I am using a Dell > Optiplex series desktop which has a 20GB of ram (Max capacity). Considering > the time it is taking my lab has plan to speed up the processing power. One > of our service provider has suggested CUDA, NVIDIA's parallel computing > architecture, for more speed. But unfortunately I am not sure whether MIRA > is CUDA enabled or not. Additionally any suggestion regarding any > COST-EFFECTIVE upgradation is much appreciated :) > > Best > > chayan > > -- > *CHAYAN ROY* > > > >