Hi All, In recent time I have assembled few genomes. Currently I am using a Dell Optiplex series desktop which has a 20GB of ram (Max capacity). Considering the time it is taking my lab has plan to speed up the processing power. One of our service provider has suggested CUDA, NVIDIA's parallel computing architecture, for more speed. But unfortunately I am not sure whether MIRA is CUDA enabled or not. Additionally any suggestion regarding any COST-EFFECTIVE upgradation is much appreciated :) Best chayan -- *CHAYAN ROY*