Did the things they mentioned -- changed the win.ini file and both TWCONF2.INI files which find showed to just have the information needed. Restarted my computer and same message "Twain already in Use." Computer recognizes scanner and so does PaperPort Version 7 but when scanner button or through software scan button and/or Twain devise button is pressed get the blankety blank message again. Even found out prior HP scanner was using a serial port and not using USB but I uninstalled that scanner program just in case and restarted computer -- still the same message "Twain already in Use." No digital camera is attached either. Any more ideas on where the conflict could be? Judith To unsub or change your email settings: //www.freelists.org/webpage/pctechtalk To access our Archives: http://groups.yahoo.com/group/PCTechTalk/messages/ //www.freelists.org/archives/pctechtalk/