-----Original Message----- From: Erin Holder <erin.holder@xxxxxxxxxxx> Sent: May 8, 2004 8:49 AM To: lit-ideas@xxxxxxxxxxxxx Subject: [lit-ideas] Re: Correction and Weight Watchers (1974) http://www.candyboots.com/wwcards.html Cool. This stuff sounds right up Roy's alley, or bagpipes as the case may = be. Check out this bio of him. http://www.dailyobjectivist.com/Heroes/RoyWalford.asp Roy Walford We don't know if what works for lab mice will also work for men, but 75-yea= r-old Roy Walford aims to find out.=20 He was 17 when he announced in his high school newspaper that life is too s= hort to do everything one could want to do=97and he has spent the rest of h= is life figuring out how to extend it. Walford's work as a medical researcher helped to show that mice live longer= on a low-calorie diet. Their typical life span is about 39 months (equival= ent to 110 human years, we're told). That tenure can be extended to as many= as 56 months if the critters are fed a restricted diet decreasing the norm= al calorie intake by 40 percent. "We've found that a 36-month-old restricte= d mouse will run a maze with the same facility as a 6-month-old normally fe= d mouse," Walford told Discover magazine (Feb. 2000). "That's a substantial= preservation of intellectual function." The hitch: it looked at first as if the mice had to start the low-cal diet = when very young for it to do them any good. But in the 1980s, Walford learn= ed that even middle-aged mice could benefit from the slashed diet so long a= s they were introduced to it gradually. Never one to restrict his theorizing to the armchair, Walford thereupon com= menced a restricted diet for himself as well. He has reduced his calorie in= take to 1500 or so a day, and sustained that regimen for the better part of= two decades. Increasing the length of life is only half the Walford life extension progr= am, though. Walford also works to achieve what he calls "sign posts"=97the = undertaking of unusual exploits that add zest and variety to life. =20 Some of Walford's sign posts: * As a recent college graduate in the late 40s, figured out how to win at t= he roulette table so he could fund a sailing trip around the world. =20 * At age 48, broke his motorcycle and a leg while attempting a wheelie on L= A's Santa Monica Boulevard. * A couple years later, took a sabbatical from UCLA to spend a year trekkin= g through India; later made the same peripatetic journey through Africa. * In 1991, now 67, Walford holed up with several colleagues in the "self-co= ntained ecosystem" of Biosphere 2. The econauts could barely harvest enough= food to survive the two-year episode (they agreed not to import any susten= ance from the outside).=20 This is a guy who doesn't save anything for the return trip, an approach no= t without risks. The scanty diet plus constant grueling labor injured his b= ack. More seriously, his nervous system was permanently damaged, apparently= as a result of nitrous oxide buildup in the enclosed atmosphere. (The effe= cts were evident only after Walford had left the Biosphere.) He can now bar= ely walk, but other than that he's in great shape. What's next for Roy Walford? He's thinking of pursuing studies in either hi= story or mathematics. "It might be interesting to try my hand at mathematic= s, because everyone assumes it's a young man's game." At 75, he's got maybe just a few more years in which to prove himself=97or = a hundred. A.A. Erin Toronto Quoting andy amago <aamago@xxxxxxxxxxxxx>: > Just as I was waking up today it came to me that in the recent fat posts,= I > wrote that a BMI of 26 or higher is obese. Wrong. 26 to 30 is overweigh= t.=20 > 30 or over is obese. The mechanism behind aging, whether it be genetic, = free > radical, infammatory, whatever, is only being guessed at. I think it's s= afe > to say death will be with us for quite a while. =20 >=20 > Argh, I just googled up Roy Walford. He died a couple of weeks ago, and = he > was only 80. Well then, live and learn. And die. So, Donal, you're rig= ht.=20 > To heck with this biochemical machine. In the battle of the Sybarites vs= . > the Spartans, Dr. Kevorkian wins. Looks like what works in laboratory > animals doesn't always translate to humans. Most likely the most we can = hope > for is to improve the quality of our lives, not the quantity. Michael > Jacobson be damned. A big bag of Nachos and brie looks like real quality= to > me. >=20 > Okay then. Where's my skirt?=20 >=20 >=20 > A.A. >=20 >=20 >=20 >=20 > ------------------------------------------------------------------ > To change your Lit-Ideas settings (subscribe/unsub, vacation on/off, > digest on/off), visit www.andreas.com/faq-lit-ideas.html >=20 --=20 Erin ------------------------------------------------------------------ To change your Lit-Ideas settings (subscribe/unsub, vacation on/off, digest on/off), visit www.andreas.com/faq-lit-ideas.html ------------------------------------------------------------------ To change your Lit-Ideas settings (subscribe/unsub, vacation on/off, digest on/off), visit www.andreas.com/faq-lit-ideas.html