I hate to bother you again, but I think u can give me quick clue. Do you know if Bioconductor support Tiling array data? or I have to write code to normalize according to your 2003 paper? Sincerely, ------- Mingqi Email:mqwu@xxxxxxxxxxxxx > The short answer is the current version of RMAExpress only supports 3' > expression arrays and also the newer Exon arrays. > > Tiling array data is not currently supported. > > Ben > > > > > On Sun, 2007-07-08 at 18:52 -0500, Mingqi Wu wrote: >> Dear All, >> >> I am new to RMAexpress. I am trying to use RMAExpress to normalize CEL >> data file from Affymetrix GeneChip microarrays. >> >> I have installed RMAExpress 0.5 on my windows XP, however I met 2 >> problem: >> >> 1. I can not load CEL file: File -> Read Unprocess Files -> CDF files >> (there is only one option for CDF file, no CEL option) >> >> 2. I tried to convert the CEL file with RMADataConv. I first choose CEL >> File Dir, then set Output dir and choose Convert, it always saying could >> not read CEL file. >> >> By the way, I use a public CEL file from following link: >> >> http://transcriptome.affymetrix.com/publication/tfbs/ >> >> *Transcription Factor Binding Sites Data* >> >> * Raw CEL Data >> >> <http://transcriptome.affymetrix.com/download/publication/tfbs_data/intensity/cel.tgz>. >> >> >> >> Could you give me some help? is the data problem or RMAexpress prolbem? >> >> Thank you so much. >> >> Sincerely, >> ----------- >> Mingqi Wu >> Email: mqwu@xxxxxxxxxxxxx >> > >