I just placed another order for the 3 pack and also for TMG for methylation! So
I did it in two separate orders, don't know if you can get the 65% off by
urdering more than one set! But hurry up it may bot last! Watch the video I
sent you very interesting about cancer and methylation issues with too much NAD+
A true lover of wisdom has hands too busy to hold on to anything! He learns by
doing and every pebble in the path becomes her teacher! Oink
On Friday, April 30, 2021, 09:09:12 PM EDT, Silver Mouse <mice42@xxxxxxxxx>
wrote:
Oh, that is a good price. Can you use the coupon more than once? I get the
Elysium brand by subscription, costs $$$480/year!
On Fri, Apr 30, 2021 at 7:16 PM Domingo Pichardo <dmarc-noreply@xxxxxxxxxxxxx>
wrote:
It is an NAD booster... very important for every cell, specially under stress!
Suplemento NMN de forma estabilizada, cápsulas de mononucleótido de
nicotinamida para apoyar antienvejecimiento, longevidad y energía, naturalmente
impulsa los niveles de NAD+ - 60 cápsulas
|
|
|
| | |
|
|
|
| |
Suplemento NMN de forma estabilizada, cápsulas de mononucleótido de nico...
Suplemento NMN de forma estabilizada, cápsulas de mononucleótido de
nicotinamida para apoyar antienvejecimiento,...
|
|
|
What Is NAD? (Why Is It Important for Health and Aging?)
What does NAD mean? It stands for nicotinamide adenine dinucleotide, a type of
coenzyme found in humans, animals, yeast and basically all living things.
Coenzymes are needed in the body to allow other enzymes to work.
A basic definition of nicotinamide adenine dinucleotide is “a cofactor found in
all living cells.” It’s involved in energy metabolism and a number of bodily
processes that allow life to be possible.
NAD+ is made up of two nucleotides, the building blocks for nucleic acids,
which form DNA.
According to Elysium — a company that sells NAD supplements and is run by “a
team of scientists, innovators, and creatives” — “NAD+ has two general sets of
reactions in the human body: helping to turn nutrients into energy as a key
player in metabolism, and working as a helper molecule for proteins that
regulate other biological activity.”
Recently studies have linked the use of an NAD supplement with benefits such as:
- Improved energy, mental clarity and alertness, due to its positive effects
of cellular processes that support cognitive function
- Improved memory and help treating Alzheimer’s disease and dementia
- Enhanced athletic performance and muscle function
- Better protection against certain cardiovascular problems
- Reduced symptoms associated with chronic fatigue syndrome
- Protection against vision loss and signs of skin aging
- Regulation of circadian rhythms and appetite
What’s the difference between NAD and NAD+?
What is NAD+, and how is its function different than that of NAD’s? The
difference all comes down to the charge of these coenzymes.
NAD+ is written with a superscript + sign because of the positive charge on one
of its nitrogen atoms. It is the oxidized form of NAD.
It’s considered “an oxidizing agent” because it accepts electrons from other
molecules.
Although they are different chemically, these terms are mostly used
interchangeably when discussing their health benefits.
Another term you may come across is NADH, which stands for nicotinamide adenine
dinucleotide (NAD) + hydrogen (H). This is also used interchangeably with NAD+
for the most part.
Both are nicotinamide adenine dinucleotides that function as either hydride
donors or hydride acceptors. The difference between these two is that that NADH
becomes NAD+ after it donates an electron to another molecule.
How Your Body Uses It (and Why It Declines with Age)
Nicotinamide adenine dinucleotide is described as a “helping molecule” because
it binds to other enzymes and causes reactions in the body that have positive
outcomes on your health.
Other factors that make this coenzyme so important for healthy aging include
its effects on sirtuin “anti-aging” proteins, mitochondrial activity, and
involvement in regulating oxidative stress (a cause of many chronic diseases)
and circadian rhythms (our “internal clocks”).
According to an article published in Scientific America, “A prominent theory of
aging holds that decaying of mitochondria is a key driver of aging.”
As mitochondria lose some of their power, this seems to contribute to diseases
and symptoms tied to aging, including heart failure, cognitive
decline/neurodegeneration and fatigue.
Mitochondria are specialized structures found in cells. They participate in
many cellular processes, including helping to extract the energy that is stored
in nutrients and transforming it into a form of energy that can power the
body’s cells.
A study in mice found that increased NAD+ levels could restore mitochondrial
function. NAD+ has a key role in mitochondrial function because it is the main
coenzyme responsible for the delivery of the electrons that are extracted from
food to the electron transport chain for ATP production.
It is therefore as important for cellular energy as ATP itself.
NAD+ and Sirtuins:
A group of proteins that are linked with anti-aging effects, called sirtuins,
rely on NAD+ to function properly. Sirtuins have been found to play a role in
regulating cellular and mitochondrial health.
Some animal studies show that they play a role in maintaining the length of
telomeres, which is linked to longevity.
In studies conducted using yeast, activation of sirtuin proteins has been shown
to help expand life span, although we still don’t know exactly how this carries
over to humans.
Another enzyme with potential anti-aging effects is called poly (ADP-Ribose)
polymerases (PARPs), which some studies shown NAD+ can also help activate.
NAD Supplement Benefits and Dosage
Molecules that can be taken in supplement form to increase NAD levels in the
body are referred to by some as “NAD boosters.”
Studies conducted over the past six decades suggest that the following are some
of the many benefits associated with taking an NAD supplement:
- Can Help Restore Mitochondrial Function
- Helps Repair Blood Vessels —A 2018 mice study found that supplementation
could aid in repair and growth of aged blood vessels. There’s also some
evidence it can help manage heart disease risk factors like high blood pressure
and high cholesterol.
- May Improve Muscle Function — One animal study conducted in 2016 found
that degenerative muscles had improved muscle function when supplemented with
NAD+ precursors.
- Potentially Helps Repair Cells and Damaged DNA — Some studies have found
evidence that NAD+ precursor supplementation leads to an increase in DNA damage
repair. NAD+ is broken down into two component parts, nicotinamide and
ADP-ribose, which combine with proteins to repair cells.
- May Help Improve Cognitive Function — Several studies conducted on mice
have found that mice treated with NAD+ precursors experienced improvements in
cognitive function, learning and memory. Findings have led researchers to
believe that NAD supplement may help protect against cognitive
decline/Alzheimer’s disease.
- May Help Prevent Age-Related Weight Gain — A 2012 study showed that when
mice fed a high-fat diet were given an NAD supplement, they gained 60 percent
less weight than they did on the same diets without the supplement. One reason
this may be true is that nicotinamide adenine dinucleotide helps regulate
production of stress- and appetite-related hormones, thanks to its effects on
circadian rhythms.
Precursors are molecules used in chemical reactions inside the body to create
other compounds. There are a number of precursors of NAD+ that result in higher
levels when you consume enough of them.
These precursors include amino acids and vitamin B3. Some of the most important
precursors for increasing NAD levels are various forms of vitamin B3,
especially NR, which is considered by some experts to be the most efficient
precursor to NAD+.
One study found that one single dose of NR could increase NAD+ levels in humans
2.7-fold. Other forms of vitamin B3 that seem to be less effective for boosting
levels are nicotinic acid and nicotinamide.
Types and Dosage Recommendations:
The precursor nicotinamide riboside (NR), also called niagen, is available in
tablet or capsule form. A typical dosage of NR supplements is about 200 to 350
milligrams, taken once or twice daily.
In studies, doses of 100, 300 and 1,000 milligrams of NR daily have been shown
to have positive effects and produce dose-dependent increases in blood levels
of NAD+.
Doctors will sometimes prescribe higher doses of NAD therapy for patients in
the form of intramuscular (IM) or intravenous (IV) NAD injections. This type of
treatment may be used to manage symptoms of Parkinson’s disease, dementia or
depression, for example.
Other Ways to Increase Levels
Humans get NAD+ from their diets, specifically from eating protein-rich foods
(foods made up of amino acids). Your diet can provide you with not only amino
acids and vitamin B3, but also other precursors of this coenzyme, including
tryptophan and nicotinamide mononucleotide (or NMN).
Here’s how to increase levels naturally (according to the Tru Niagen website):
- Consume cow’s milk, yeast and beer, which research shows all contain small
amounts of NAD precursors.
- Consume high-protein foods.
- Consider trying the keto diet to increase ketone levels, which may
increase NAD levels, according to studies.
- Exercise regularly.
- Incorporate intermittent fasting into your routine.
- Avoid high alcohol intake.
Precautions and Side Effects
NAD supplement options are generally well-tolerated and don’t seem to pose much
risk for side effects when used for durations of about 12 to 24 weeks. Certain
side effects are still possible, however, and may include nausea, fatigue,
headaches, diarrhea, stomach discomfort and indigestion.
Final Thoughts
- What is NAD? It stands for nicotinamide adenine dinucleotide, which is a
coenzyme found in cells of all living beings.
- NAD supplement treatments have gained attention recently as potential
anti-aging compounds.
- Nicotinamide riboside (NR) seems to be the most important precursor of
nicotinamide adenine dinucleotide that helps increase levels. NR is an
alternative form of vitamin B3 that can be taken as a supplement.
- Here’s how to increase levels naturally: Consume cow’s milk, yeast and
beer (in moderation); eat foods with protein and B vitamins; fast; exercise
regularly; avoid high alcohol consumption.
GET FREE
A true lover of wisdom has hands too busy to hold on to anything! He learns by
doing and every pebble in the path becomes her teacher! Oink
--
<:3 )~