thanks, but I already use beet root powder and nearly every day
have broccoli, dark green vegetables, such as spinach, Swiss chard, mustard
greens, beet greens and kale. So I think I am good on the tmg front.
https://www.amazon.com/dp/B017KYQCFU/ref=sspa_dk_detail_3
On Fri, Apr 30, 2021 at 9:14 PM Domingo Pichardo <
dmarc-noreply@xxxxxxxxxxxxx> wrote:
Seems like you would also need to buy this products "TMG", along with NMN
to provide methyl donors as NAD+ uptick may decrease methyl donors! See
video below......
https://naturalhealingnews.com/trimethylglycine-tmg-to-the-rescue/
BulkSupplements.com Betaine Anhydrous Trimethylglycine (TMG) Powder -
Gallbladder Supplements (1 Kilogram)
<https://www.amazon.com/dp/B00GW6T0O8?psc=1&smid=A8MA32QEVO3GI&ref_=chk_typ_imgToDp>
$22.96
BulkSupplements.com Betaine Anhydrous Trimethylglycine (TMG) Powder - Ga...
BulkSupplements.com Betaine Anhydrous Trimethylglycine (TMG) Powder -
Gallbladder Supplements (1 Kilogram)
<https://www.amazon.com/dp/B00GW6T0O8?psc=1&smid=A8MA32QEVO3GI&ref_=chk_typ_imgToDp>
Nicotinamide Mononucleotide (NMN) Anti Aging Supplement 2020
<https://www.youtube.com/watch?v=krsHqlNy8R8>
Nicotinamide Mononucleotide (NMN) Anti Aging Supplement 2020
<https://www.youtube.com/watch?v=krsHqlNy8R8>
A true lover of wisdom has hands too busy to hold on to anything! He
learns by doing and every pebble in the path becomes her teacher! Oink
----- Forwarded Message -----
*From:* Domingo Pichardo <dpichardo3@xxxxxxxxxxx>
*Sent:* Friday, April 30, 2021, 07:15:38 PM EDT
*Subject:* I just orfered this pack of three NMN supplement! It's 65% off
at Amazon right now.... very good deal!
It is an NAD booster... very important for every cell, specially under
stress!
Suplemento NMN de forma estabilizada, cápsulas de mononucleótido de
nicotinamida para apoyar antienvejecimiento, longevidad y energía,
naturalmente impulsa los niveles de NAD+ - 60 cápsulas
<https://www.amazon.com/dp/B092ZSN7VZ?psc=1&smid=ATRCSPOVKQ3YO&ref_=chk_typ_imgToDp>
Suplemento NMN de forma estabilizada, cápsulas de mononucleótido de nico...
Suplemento NMN de forma estabilizada, cápsulas de mononucleótido de
nicotinamida para apoyar antienvejecimiento,...
<https://www.amazon.com/dp/B092ZSN7VZ?psc=1&smid=ATRCSPOVKQ3YO&ref_=chk_typ_imgToDp>
What Is NAD? (Why Is It Important for Health and Aging?)
What does NAD mean? It stands for nicotinamide adenine dinucleotide, a
type of coenzyme found in humans, animals, yeast and basically all living
things.
Coenzymes are needed in the body to allow other enzymes to work.
A basic definition
<https://www.elysiumhealth.com/en-us/knowledge/science-101/everything-you-need-to-know-about-nicotinamide-adenine-dinucleotide-nad>
of
nicotinamide adenine dinucleotide is “a cofactor found in all living
cells.” It’s involved in energy metabolism and a number of bodily processes
that allow life to be possible.
NAD+ is made up of two nucleotides, the building blocks for nucleic acids,
which form DNA.
According to Elysium <https://www.elysiumhealth.com/en-us/> — a company
that sells NAD supplements and is run by “a team of scientists, innovators,
and creatives” — “NAD+ has two general sets of reactions in the human body:
helping to turn nutrients into energy as a key player in metabolism, and
working as a helper molecule for proteins that regulate other biological
activity.”
Recently studies have linked the use of an NAD supplement with benefits
such as:
- Improved energy, mental clarity and alertness, due to its positive
effects of cellular processes that support cognitive function
- Improved memory and help treating Alzheimer’s disease and dementia
- Enhanced athletic performance and muscle function
- Better protection against certain cardiovascular problems
- Reduced symptoms associated with chronic fatigue syndrome
<https://draxe.com/health/chronic-fatigue-syndrome/>
- Protection against vision loss and signs of skin aging
- Regulation of circadian rhythms and appetite
What’s the difference between NAD and NAD+?
What is NAD+, and how is its function different than that of NAD’s? The
difference all comes down to the charge of these coenzymes.
NAD+ is written with a superscript + sign because of the positive charge
on one of its nitrogen atoms. It is the oxidized form of NAD.
It’s considered “an oxidizing agent” because it accepts electrons from
other molecules.
Although they are different chemically, these terms are mostly used
interchangeably when discussing their health benefits.
Another term you may come across is NADH, which stands for nicotinamide
adenine dinucleotide (NAD) + hydrogen (H). This is also used
interchangeably with NAD+ for the most part.
Both
<https://www.sciencedirect.com/topics/neuroscience/nicotinamide-adenine-dinucleotide>
are nicotinamide adenine dinucleotides that function as either hydride
donors or hydride acceptors. The difference between these two is that
that NADH becomes NAD+ after it donates an electron to another molecule.
How Your Body Uses It (and Why It Declines with Age)
Nicotinamide adenine dinucleotide is described as a “helping molecule”
because it binds to other enzymes and causes reactions in the body that
have positive outcomes on your health.
Other factors that make this coenzyme so important for healthy aging
include its effects on sirtuin “anti-aging” proteins, mitochondrial
activity, and involvement in regulating oxidative stress
<https://www.ncbi.nlm.nih.gov/pubmed/27051562> (a cause of many chronic
diseases) and circadian rhythms (our “internal clocks”).
According to an article published in *Scientific America*
<https://blogs.scientificamerican.com/guest-blog/beyond-resveratrol-the-anti-aging-nad-fad/>,
“A prominent theory of aging holds that decaying of mitochondria is a key
driver of aging.”
As mitochondria lose some of their power, this seems to contribute to
diseases and symptoms tied to aging, including heart failure, cognitive
decline/neurodegeneration and fatigue.
Mitochondria are specialized structures found in cells. They participate
in many cellular processes, including helping to extract the energy that is
stored in nutrients and transforming it into a form of energy that can
power the body’s cells.
A study <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963347/> in mice
found that increased NAD+ levels could restore mitochondrial
<https://draxe.com/health/mitochondria/> function. NAD+ has a key role in
mitochondrial function because it is the main coenzyme responsible for the
delivery of the electrons that are extracted from food to the electron
transport chain for ATP production.
It is therefore as important for cellular energy as ATP itself.
NAD+ and Sirtuins:
A group of proteins that are linked with anti-aging effects, called
sirtuins, rely on NAD+ to function properly. Sirtuins have been found to
play a role in regulating cellular and mitochondrial health.
Some animal studies show that they play a role in maintaining the length
<https://www.ncbi.nlm.nih.gov/pubmed/18337721/> of telomeres, which is
linked to longevity.
In studies conducted using yeast, activation of sirtuin proteins has been
shown to help expand life span, although we still don’t know exactly how
this carries over to humans.
Another enzyme with potential anti-aging effects is called poly
(ADP-Ribose) polymerases <https://www.ncbi.nlm.nih.gov/pubmed/28537485>
(PARPs),
which some studies shown NAD+ can also help activate.
NAD Supplement Benefits and Dosage
Molecules that can be taken in supplement form to increase NAD levels in
the body are referred to
<https://khn.org/news/a-fountain-of-youth-pill-sure-if-youre-a-mouse/> by
some as “NAD boosters.”
Studies conducted over the past six decades suggest that the following are
some of the many benefits associated with taking an NAD supplement:
- Can Help Restore Mitochondrial Function
- Helps Repair Blood Vessels —A 2018 mice study
<https://news.mit.edu/2018/study-suggests-method-boost-growth-blood-vessels-muscle-0322>
found
that supplementation could aid in repair and growth of aged blood vessels.
There’s also some evidence it can help manage heart disease risk factors
like high blood pressure and high cholesterol.
- May Improve Muscle Function — One animal study conducted in 2016
found that degenerative muscles had improved muscle function when
supplemented with NAD+ precursors.
- Potentially Helps Repair Cells and Damaged DNA — Some studies
<https://www.ncbi.nlm.nih.gov/pubmed/27308492> have found evidence
that NAD+ precursor supplementation leads to an increase in DNA damage
repair. NAD+ is broken down into two component parts, nicotinamide and
ADP-ribose, which combine with proteins to repair cells.
- May Help Improve Cognitive Function — Several studies
<https://www.ncbi.nlm.nih.gov/pubmed/23312803> conducted on mice
have found that mice treated with NAD+ precursors experienced improvements
in cognitive function, learning and memory. Findings
<https://www.ncbi.nlm.nih.gov/pubmed/17168650> have led researchers to
believe that NAD supplement may help protect against cognitive
decline/Alzheimer’s disease.
- May Help Prevent Age-Related Weight Gain — A 2012 study
<https://www.ncbi.nlm.nih.gov/pubmed/22682224> showed that when mice
fed a high-fat diet were given an NAD supplement, they gained 60 percent
less weight than they did on the same diets without the supplement. One
reason this may be true is that nicotinamide adenine dinucleotide helps
regulate production of stress- and appetite-related hormones, thanks to its
effects on circadian rhythms.
Precursors are molecules used in chemical reactions inside the body to
create other compounds. There are a number of precursors of NAD+ that
result in higher levels when you consume enough of them.
These precursors include amino acids and vitamin B3
<https://draxe.com/nutrition/niacin-side-effects/>. Some of the most
important precursors for increasing NAD levels are various forms of vitamin
B3, especially NR, which is considered by some experts to be the most
efficient precursor <https://www.ncbi.nlm.nih.gov/pubmed/27721479>to
NAD+.
One study <https://www.ncbi.nlm.nih.gov/pubmed/27721479> found that one
single dose of NR could increase NAD+ levels in humans 2.7-fold. Other
forms of vitamin B3 that seem to be less effective for boosting levels are
nicotinic acid and nicotinamide.
Types and Dosage Recommendations:
The precursor nicotinamide riboside
<https://draxe.com/nutrition/nicotinamide-riboside/> (NR), also called
niagen, is available in tablet or capsule form. A typical dosage of NR
supplements is about 200 to 350 milligrams, taken once or twice daily.
In studies, doses of 100, 300 and 1,000 milligrams of NR daily have been
shown to have positive effects and produce dose-dependent increases in
blood levels of NAD+.
Doctors will sometimes prescribe higher doses of NAD therapy for patients
in the form of intramuscular (IM) or intravenous (IV) NAD injections. This
type of treatment may be used to manage symptoms of Parkinson’s disease,
dementia <https://draxe.com/health/dementia/> or depression, for example.
Other Ways to Increase Levels
Humans get NAD+ from their diets, specifically from eating protein-rich
foods (foods made up of amino acids). Your diet can provide you with not
only amino acids <https://draxe.com/nutrition/essential-amino-acids/> and
vitamin B3, but also other precursors of this coenzyme, including
tryptophan and nicotinamide mononucleotide (or NMN).
Here’s how to increase levels naturally (according to the Tru Niagen
website
<https://blog.truniagen.com/home/2018/3/20/do-nad-supplements-really-work>
):
- Consume cow’s milk, yeast and beer, which research
<https://www.ncbi.nlm.nih.gov/pubmed/25974041> shows all contain small
amounts of NAD precursors.
- Consume high-protein foods.
<https://draxe.com/nutrition/protein-foods/>
- Consider trying the keto diet
<https://draxe.com/nutrition/guide-to-keto-diet-for-beginners/> to
increase ketone levels, which may increase NAD levels, according to
studies.
<https://www.sciencedirect.com/science/article/abs/pii/S0306452206016617>
- Exercise regularly.
- Incorporate intermittent fasting
<https://draxe.com/nutrition/intermittent-fasting-benefits/> into your
routine.
- Avoid high alcohol intake.
Precautions and Side Effects
NAD supplement options are generally well-tolerated and don’t seem to pose
much risk for side effects when used for durations of about 12 to 24 weeks.
Certain side effects are still possible, however, and may include nausea,
fatigue, headaches, diarrhea, stomach discomfort and indigestion.
Final Thoughts
- What is NAD? It stands for nicotinamide adenine dinucleotide, which
is a coenzyme found in cells of all living beings.
- NAD supplement treatments have gained attention recently as
potential anti-aging compounds.
- Nicotinamide riboside (NR) seems to be the most important precursor
of nicotinamide adenine dinucleotide that helps increase levels. NR is an
alternative form of vitamin B3 that can be taken as a supplement.
- Here’s how to increase levels naturally: Consume cow’s milk, yeast
and beer (in moderation); eat foods with protein and B vitamins; fast;
exercise regularly; avoid high alcohol consumption.
[image: Josh Axe]
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A true lover of wisdom has hands too busy to hold on to anything! He
learns by doing and every pebble in the path becomes her teacher! Oink
