Hello bastien, Afetr resolving all the errors before in the config file , I had finally left mira to run on April 30 which finished finally on May 12th but with error ..:( I really wish you could help me with this, ERROR, in the output txt file Thank you for noticing that this is *NOT* a crash, but a controlled program stop. CWD: /tmp1/monithesis/mira/mira3/mira4 Thank you for noticing that this is *NOT* a crash, but a controlled program stop. Fatal error (may be due to problems of the input data or parameters): "Could not write anymore to skimhit save5. Disk full? Changed permissions?" ->Thrown: void Skim::selectPotentialHitsForSave2(const int8 direction, const uint3 2 actreadid, cfh_threaddata_t & cfhd) ->Caught: void Skim::threadloop(const uint32 threadnr) Aborting process, probably due to error in the input data or parametrisation. Please check the output log for more information. For help, please write a mail to the mira talk mailing list. Subscribing / unsubscribing to mira talk, see: //www.freelists.org/list/mira_ talk Fatal error (may be due to problems of the input data or parameters): "Could not write anymore to skimhit save5. Disk full? Changed permissions?"CWD: ->Thrown: /tmp1/monithesis/mira/mira3/mira4void Skim::selectPotentialHitsForSave2( const int8 direction, const uint32 actreadid, cfh_threaddata_t & cfhd) ->Caught: void Skim::threadloop(const uint32 threadnr) Aborting process, probably due to error in the input data or parametrisation. Please check the output log for more information. For help, please write a mail to the mira talk mailing list. Subscribing / unsubscribing to mira talk, see: //www.freelists.org/list/mira_ talk Thank you for noticing that this is *NOT* a crash, but a controlled program stop. CWD: /tmp1/monithesis/mira/mira3/mira4 Thank you for noticing that this is *NOT* a crash, but a controlled program stop. Fatal error (may be due to problems of the input data or parameters): "Could not write anymore to skimhit save5. Disk full? Changed permissions?" ->Thrown: void Skim::selectPotentialHitsForSave2(const int8 direction, const uint3 2 actreadid, cfh_threaddata_t & cfhd) ->Caught: void Skim::threadloop(const uint32 threadnr) Aborting process, probably due to error in the input data or parametrisation. Please check the output log for more information. For help, please write a mail to the mira talk mailing list. Subscribing / unsubscribing to mira talk, see: //www.freelists.org/list/mira_ talk CWD: /tmp1/monithesis/mira/mira3/mira4 Thank you for noticing that this is *NOT* a crash, but a controlled program stop. Fatal error (may be due to problems of the input data or parameters): ****Also I found out tht it created files terabytes in the tmp folder.....I really don't understand what to do next*** *#manifest file for mira4* project=mira4 job=mapping,genome,accurate parameters = -GE:not=32\ COMMON_SETTINGS -AS:nop=1\ -MI:somrnl=0\ -SK:mnr=no:mmhr=1\ SOLEXA_SETTINGS -CO:msr=no readgroup=illuminaassembly data = mira4_backbone_in.fna as_reference strain = mira4_bft parameters = COMMON_SETTINGS -DI:trt = /tmp2/tmp default_qual = 30 readgroup = solexareads data = /ctx/tmp1/monithesis/mira/mira3/mira4/mira41_in.solexa.fastq /ctx/tmp1/mon ithesis/mira/mira3/mira4/mira42_in.solexa.fastq technology = solexa templatesize= 250 750 infoonly segment_placement= ---> <--- infoonly strain = mira4_sol "Could not write anymore to skimhit save5. Disk full? Changed permissions?" ->Thrown: void Skim::selectPotentialHitsForSave2(const int8 direction, const uint3 2 actreadid, cfh_threaddata_t & cfhd) ->Caught: void Skim::threadloop(const uint32 threadnr) Aborting process, probably due to error in the input data or parametrisation. Please check the output log for more information. For help, please write a mail to the mira talk mailing list. Subscribing / unsubscribing to mira talk, see: //www.freelists.org/list/mira_ talk CWD: /tmp1/monithesis/mira/mira3/mira4 Thank you for noticing that this is *NOT* a crash, but a controlled program stop. **Also I there was no output file was produced, instead there was a hidden output txt file , I had run mira using command "nohup mira mira4_manifest.conf >$log4_assembly.txt"..however i did not get this log4_assembly.txt file , instead i got a hidden .txt file. Please guide me, Monitha "