It's good to get your input on this. My understanding is the Canadian
government ( at the time) told the drug companies that they couldn't take
large profits from drugs manufactured in Canada. The result is the
companies went elsewhere so they could
produce more profitably. Now we don't have the manufacturing capabilities
as it has gone off shore.
Is this valid?
Wynn
On Sun, Feb 7, 2021 at 11:22 AM akfarmilo2 <akfarmilo2@xxxxxxxxxxxx> wrote:
Good Sunday Larry and Bob and all
Interesting interview. The history of Canada becoming completely
dependent on others for our "value added" (read costly) goods is a sad
one. I think this is driven by a perception of a small market, supposed
efficiencies of scale in larger markets and compounded by low risk
tolerance in investing and lack of Canafian based venture capital.
We have as a culture discounted Canadian ingenuity and creativity to the
extent that few people who are able are prepared to support early stage
translation of ideas into the commercial world.
There are enough notable and brilliant Canadian successes to demonstrate
that it can be done. We need to believe in ourselves.
Vaccine production is an example that has been driven to the forefront.
Vaccine production for the Canadian market alone is probably not normally
sustainable, but creating a Contract Manufacturing Organization (CMO) to
produce RNA therapies in general would be a very good bet to succeed.
First, they would be selling services to a globsl market which is seeking
reliable alternate suppliers minimally sensitive to global politicsl
vagaries. Canada has the global reputation that would support our role.
Second, vaccines are only the thin edge of the wedge when it comes to RNA
therapies. Conceivably any disease in which a protein is missing,
defective, over- or under-produced could potentially be targeted by RNA
therapy. Think diabetes or breast cancer as examples. There are other
novel RNA therapies for similar diseases now at or approaching regulatory
approvals.
Conflict of interest statement: I am working to build a company with a
novel way of making RNA therapies more stable. I am quite passionate and
convinced that this can be done. Someone will do this.....I would love it
to be a Canadian success.
YITBOS,
Jim
Sent from my Samsung device over Bell's LTE network.
-------- Original message --------
From: Bob Thomlinson <bthomlinson@xxxxxxxxx>
Date: 07-02-2021 11:08 (GMT-05:00)
To: DSP-EA-General@xxxxxxxxxxxxx
Subject: RE: Astro Zeneca Vaccine
Larry,
I finally had the time to watch your Sir John Bell interview video and
yes, it was interesting.
Too bad the interviewer kept trying to get Bell to say that Canada had
screwed up. It gets tiring hearing the media constantly trying to play
Wack-a-Mole and find fault with every decision made in the past that didn’t
work out as expected.
Even though the interviewer didn’t ask what we should be doing going
forward, Bell gave an opinion that seems to align with the current efforts
to manufacture at home.
Thanks for this,
Bob T
*From:* Wynn Payne <wynn.payne@xxxxxxxxx>
*Sent:* February 4, 2021 11:24 AM
*Subject:* Fwd: Astro Zeneca Vaccine
---------- Forwarded message ---------
From: *Larry Kolmatycki* <lkolmatycki@xxxxxxxxxxx>
Date: Thu, Feb 4, 2021 at 9:15 AM
Subject: Astro Zeneca Vaccine
To: traveler1031@xxxxxxxxxxx <traveler1031@xxxxxxxxxxx>
Hello,
I received this from a friend. It is CTV interview with Sir John Bell of
Oxford University in England. He is a graduate of the U of A (1975). He was
instrumental in the development of Astro Zeneca. He describes the United
Kingdom’s situation and it raises many questions about what we are doing.
https://northernontario.ctvnews.ca/video?clipId=2130105
<https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fnorthernontario.ctvnews.ca%2Fvideo%3FclipId%3D2130105&data=04%7C01%7C%7C1bc0134f342746fc665f08d8c8c6f854%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637480104194256720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=0uai%2B5B4epjzkEo8ExXgIKTsG45Lop%2FBGLzhaiq%2BijM%3D&reserved=0>
Larry
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