Got my two injections of Moderna vaccine at my clinichere in Fresno. Half the
physiciansdeclined the injection but they order the vaccine for their patients
all the time . Go figure. The localpharmacies will soon be injecting the
general public. Monitor CVS.COM for dates , locations and availiability.You
might be able to drive down and geta shot. They are all free. Tell them
youare an illegal immigrant farm worker from Canada providing an ‘essential
service’ and you mightget an injection right away. Mexican nationalsare getting
the vaccine. My 94 y/o father has covid in a Edmonton nursing homewhere 55
residents have died so far. Canada did not anticipate slowdistribution and
should have tried to produce their own.
Paul kruper
On Sunday, February 7, 2021, 01:36:16 PM PST, akfarmilo2
<akfarmilo2@xxxxxxxxxxxx> wrote:
You are right about the buying groups Bob. They are a big reason the drug
costs (and ptofits) are lower in some countries.
The bickering could perhaps be avoided if the company did not need any Federal
support The company could then select the site by normal corporate factors
such as land, labor, transportation, skills, etc.In general government and
business are not a good cultural match for a partnership. If used, govt
support should complement a business plan and not define the business plan.
Sorry....I got off topic.....The End.Jim
Sent from my Samsung device over Bell's LTE network.
-------- Original message --------
From: Bob Thomlinson <bthomlinson@xxxxxxxxx>
Date: 07-02-2021 16:10 (GMT-05:00)
To: dsp-ea-general@xxxxxxxxxxxxx
Subject: RE: Astro Zeneca Vaccine
Jim,
My understanding is that our drug costs are lower because we have provincial
agencies that do all the buying for the provinces and some provinces have
banded together as a buying group. We get lower prices because we have a small
number of buyers who cab buy in larger volumes (“larger” being relative).
The situation in other countries is different. I believe the bigger Health
Management Organizations in the USA do central buying but there are also
thousands of independent privately owned hospitals and pharmaceutical
distributors who order their own products. The National Health Service (NHS) in
Britain is the central buyer for all the health services except their allowed
private medical hospitals and services.
Britain has a larger population than Canada, so centralized purchasing with a
national scope is going to swing better deals than our small province wide
approach. Britain would also be able to make decisions quickly to support
manufacturing vaccines. They don’t need the provincial negotiations that Canada
would need to get support and agreement. Canada pays for health costs, but the
actual service delivery is within provincial jurisdiction. We would have had
the usual bickering about where to build manufacturing capability and which
province would get the jobs.
I hope Don Denmark comments on this. He seems well placed to know what is
happening in the USA.
Cheers,
Bob T
From: dsp-ea-general-bounce@xxxxxxxxxxxxx <dsp-ea-general-bounce@xxxxxxxxxxxxx>
On Behalf Of akfarmilo2
Sent: February 7, 2021 12:19 PM
To: dsp-ea-general@xxxxxxxxxxxxx
Subject: Re: Astro Zeneca Vaccine
Hi Wynn, I don't know about the approach of restricting profits but I do know
the Canadian mkt does not pay as much for drugs as the US mkt does. I also
know that regulatory cost is pretty much the same in both countries so return
on investment can be far higher in US (for example). Has the same effect as an
outright profit restriction would.
...Jim
Sent from my Samsung device over Bell's LTE network.
-------- Original message --------
From: Wynn Payne <wynn.payne@xxxxxxxxx>
Date: 07-02-2021 13:41 (GMT-05:00)
To: Delta Sig master list <dsp-ea-general@xxxxxxxxxxxxx>
Subject: Re: Astro Zeneca Vaccine
It's good to get your input on this. My understanding is the Canadian
government ( at the time) told the drug companies that they couldn't take large
profits from drugs manufactured in Canada. The result is the companies went
elsewhere so they could
produce more profitably. Now we don't have the manufacturing capabilities as it
has gone off shore.
Is this valid?
Wynn
On Sun, Feb 7, 2021 at 11:22 AM akfarmilo2 <akfarmilo2@xxxxxxxxxxxx> wrote:
Good Sunday Larry and Bob and all
Interesting interview. The history of Canada becoming completely dependent on
others for our "value added" (read costly) goods is a sad one. I think this is
driven by a perception of a small market, supposed efficiencies of scale in
larger markets and compounded by low risk tolerance in investing and lack of
Canafian based venture capital.
We have as a culture discounted Canadian ingenuity and creativity to the extent
that few people who are able are prepared to support early stage translation of
ideas into the commercial world.
There are enough notable and brilliant Canadian successes to demonstrate that
it can be done. We need to believe in ourselves.
Vaccine production is an example that has been driven to the forefront.
Vaccine production for the Canadian market alone is probably not normally
sustainable, but creating a Contract Manufacturing Organization (CMO) to
produce RNA therapies in general would be a very good bet to succeed. First,
they would be selling services to a globsl market which is seeking reliable
alternate suppliers minimally sensitive to global politicsl vagaries. Canada
has the global reputation that would support our role. Second, vaccines are
only the thin edge of the wedge when it comes to RNA therapies. Conceivably
any disease in which a protein is missing, defective, over- or under-produced
could potentially be targeted by RNA therapy. Think diabetes or breast cancer
as examples. There are other novel RNA therapies for similar diseases now at
or approaching regulatory approvals.
Conflict of interest statement: I am working to build a company with a novel
way of making RNA therapies more stable. I am quite passionate and convinced
that this can be done. Someone will do this.....I would love it to be a
Canadian success.
YITBOS,
Jim
Sent from my Samsung device over Bell's LTE network.
-------- Original message --------
From: Bob Thomlinson <bthomlinson@xxxxxxxxx>
Date: 07-02-2021 11:08 (GMT-05:00)
To: DSP-EA-General@xxxxxxxxxxxxx
Subject: RE: Astro Zeneca Vaccine
Larry,
I finally had the time to watch your Sir John Bell interview video and yes, it
was interesting.
Too bad the interviewer kept trying to get Bell to say that Canada had screwed
up. It gets tiring hearing the media constantly trying to play Wack-a-Mole and
find fault with every decision made in the past that didn’t work out as
expected.
Even though the interviewer didn’t ask what we should be doing going forward,
Bell gave an opinion that seems to align with the current efforts to
manufacture at home.
Thanks for this,
Bob T
From: Wynn Payne <wynn.payne@xxxxxxxxx>
Sent: February 4, 2021 11:24 AM
Subject: Fwd: Astro Zeneca Vaccine
---------- Forwarded message ---------
From: Larry Kolmatycki <lkolmatycki@xxxxxxxxxxx>
Date: Thu, Feb 4, 2021 at 9:15 AM
Subject: Astro Zeneca Vaccine
To: traveler1031@xxxxxxxxxxx <traveler1031@xxxxxxxxxxx>
Hello,
I received this from a friend. It is CTV interview with Sir John Bell of Oxford
University in England. He is a graduate of the U of A (1975). He was
instrumental in the development of Astro Zeneca. He describes the United
Kingdom’s situation and it raises many questions about what we are doing.
https://northernontario.ctvnews.ca/video?clipId=2130105
Larry
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