% Negation Character

Hi Folks,
I'm migrating from Sybase to Oracle, on Sybase I had a function with and update: 

   update XYZ
   set flag = flag &~4589
Now on Sybase "~" character is used as negative character, so the query do this (on sybase): Update the table XYZ on the Flag column with the bitand beteewn flag and 4589 if the binary bit corresponding to this value is not ON ...
How can I do this on Oracle?? I mean is there any negation character on oracle similiar to ~ on Sybase?? I been searching but I still don't find anything helpful, could someone advice about this?? 

Thanks in advanced.

Cheers, Citlali

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