Yep - I'm having the same experience. I just found the problem in the Microsoft knowledgebase: Server Publishing Rules Intermittently Fail Q307784 > I have a web server on the internal side of my ISA server that is > published using a server publishing rule. (I do this so that we can > generate weblogs) This works very well, accept sporadically the websites > are inaccessible to the outside of the firewall. To fix the problem we > have found that we have to disable the rule for that server, then > re-enable it and everything works fine after that. We have other web > servers that are published in an identical manner and never have this > problem. > > BTW, nothing strange is being reported in the event logs on the ISA server > when this happens. > > Any ideas anyone?