[ SHOWGSD-L ] Please support critical GSDM research

  • From: "David Fritsche" <d_fritsche@xxxxxxxxxx>
  • To: <Pinehillgsds@xxxxxxx>, <melanagsd@xxxxxxxxxxxxx>, <LinronsKnl@xxxxxxx>, <showgsd-l@xxxxxxxxxxxxx>
  • Date: Mon, 16 Mar 2009 15:35:48 -0700


> Me too.  Had a gentleman call w/ questions re the OFA web site (they
> apparently have recognized the test for our breed).  Would love a 
> definitive answer,
> even if that answer is "the DNA test on the OFA's site is 
> inconclusive".
>
> Kathy, member GSDCA, DVGSDC

There is a controversy raging and there are differences of opinion on 
the DM cause and testing for GSD's.

I am not a scientist and do not have the qualifications to give an 
authoritative conclusion, so each person will have to make up their 
own minds. There is a DM list you can join at: 
http://pets.groups.yahoo.com/group/DMdogs/

There are also a great list of research finding on the OFA site at: 
http://www.offa.org/dnatesting/

Basically the controversy is that the U of Missouri team headed by Dr. 
Coates worked from a hypothesis that DM is basically the equivalent of 
ALS in humans and successfully found the gene that OFA is testing for. 
Dr. Clemmons flash test is looking for another gene as his hypothesis 
is that DM is not equivalent to ALS. At least this is my understanding 
which is always suspect and should be ignored at all cost.

These two sites will give more research findings than you can possibly 
read in one setting.

Good luck, and may we find the right test and eliminate this disease 
by any means.
Dave 

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