On Friday 09 September 2011 07:40:04 000.calabi.yau.000@xxxxxxxxxxxxxx wrote: > have you tried error correcting the data using: > > SOLiD™ Accuracy Enhancement Tool => > http://solidsoftwaretools.com/gf/project/saet/ > > It is often recommended on the ABySS assembler mailing list for SOLiD data > prior to assembly. => http://www.bcgsc.ca/platform/bioinfo/software/abyss > I haven't used SOLiD data before, but maybe this helps you. Maybe ABySS is > also an alternative to Velvet in your case... Now that's something potentially extremely useful and I can understand why it is recommended. Actually that's the tool that might change my position on supporting SOLiD ... has anyone here experience with the usefulness of it? B.