Might be of interest.
For YETI
Debabrata Phukon
---------- Forwarded message ---------
From: Mohan Patel <monapatelpgatti@xxxxxxxxx>
Date: Mon, 10 Jun 2019, 10:13 am
Subject: Re: JRF Vacancy
To: YETI <meet.yeti@xxxxxxxxx>
*Dear Sir, *
*Please circulate it in Yeti*
*Thanking you,*
*Mohan*
*The University *of T*rans-Disciplinary Health Sciences and Technology
(TDU)*
*Position: *JRF (1 No.)
*Project: Multi-omic approaches and mass spectrometry based tissue
metabolite imaging towards understanding metabolites localisation and
metabolic pathways in specific cell/tissues of key medicinal
plant, Dysoxylum binectariferum. *
*Funding Agency: *SERB, DST, Govt. of India
*Duration:* 3 years
*Fellowship:* As per SERB, DST norms
*Requirement: *immediately
*Description: *Advanced multi-omics technologies provide revolutionary
strategies to study complex biological processes, e.g. to systematically
decipher biosynthetic pathways to mechanistically challenging, structurally
complex, widely used plant medicinals that cannot be economically
synthesized. A multi-omics strategy is proposed to deduce biosynthetic
pathway to rohitukine, a chromone alkaloid, widely used in cancer
treatment. Distinct cell types involved *in planta*will be identified using
mass spectrometry based metabolite imaging *in situ*and laser microscope
dissection. Knowledge gained can be applied to developing synthetic biology
approaches in order to obtain new sources of these compounds in other host
systems.
*Skills sets required*
· Molecular and biochemical techniques
· Isolation, purification and structural characterization of
secondary metabolitesExperience in Chromatographic techniques like HPLC,
GCMS and LCMS
· Experience in RNA isolation, Synthesis of cDNA. PCR, RT-PCR,
qPCR, cloning and transformation.
· Bioinformatics: transcriptome analysis
*References.*
· *Mohana Kumara P*, Srimany A, Arunan S, Ravikanth G, Uma Shaanker
R, Pradeep T. *2016*Desorption Electrospray Ionization (DESI) Mass
Spectrometric Imaging of the Distribution of Rohitukine in the
Seedling of *Dysoxylum
binectariferum*Hook. F. PLoS ONE 11(6): e0158099. doi: 10.1371/journal.pone
.0158099*IF: 3.54*
· *Mohana Kumara P**, *AmitavaSrimany ,Ravikanth G , Uma Shaanker,
R. Pradeep, T.*2015*Ambient ionization mass spectrometry imaging of
rohitukine, a chromone anti-cancer alkaloid, during seed development
in *Dysoxylum
binectariferum*Hook. F (Meliaceae). Phytochemistry. Volume 116, 104-110. *IF:
3.35*
see this link for details: https://mohanmultiomics.wordpress.com/
*To apply:* Send out the detailed CV. All selected candidates will be
informed. No TA/DA will be provided. Interested candidates to send their cv
to mohan.kumar@xxxxxxxxxx and cc to hr@xxxxxxxxxx
*Start date:* July 2019.
*Duration:* One-year contract, extendable up to next two years based on
performance.
Send out the detailed CV. All selected candidates will be informed. No
TA/DA will be provided. Interested candidates to send their cv to
mohan.kumar@xxxxxxxxxx and hr@xxxxxxxxxx
--
*Dr. Mohana Kumara P*
*Assistant Professor*
Centre for Ayurveda Biology and Holistic Nutrition (CABHN) at TDU:
http://tdu.edu.in/home/cab/ ;<http://www.tdu.edu.in/genomics>
https://mohanmultiomics.wordpress.com/
*The *
*University of Trans-Disciplinary Health Sciences and Technology (TDU)*
tdu.edu.in <http://www.tdu.edu.in/> Ph; +91-80-28568000, Extn;153/144;
+91-80-28568878
Phone:91-9790464058;91-8124045644
