Duas posições de doutorado em biologia evolutiva. André
Uppsala University hereby invites applications for 2 Ph.D. positions in Animal
Ecology at the Department of Ecology and Genetics, Evolutionary Biology Centre
(EBC) with an application deadline of March 15.
Position 1: The Evolution of Adaptive Epigenetic Inheritance, in the lab of Dr.
Martin Lind
Position 2: Causes and Consequences of Variation in Mutation Rate, in the lab
of Dr. David Berger
The two advertised positions are independent. Applicants that are interested in
both positions should submit two separate applications.
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POSITION 1 – The Evolution of Adaptive Epigenetic Inheritance
The belief that the genetic code is the sole basis for biological inheritance
has been challenged by the discovery of trans-generational epigenetic
inheritance, where environmentally induced phenotypes are inherited for several
generations by factors that determine how DNA is read. However, the adaptive
significance of a complementary inheritance system that is induced by the
environment is enigmatic.
The applicant will investigate the evolution of adaptive epigenetic and
trans-generational inheritance during adaptation to new environments (high or
fluctuating temperature) in the powerful laboratory Caenorhabditis remanei
nematode model system. We will use a combination of experimental evolution,
trans-generational phenotypic assays of life history traits (fitness, growth,
development, lifespan) and gene expression approaches, including analyses of
already existing lines. The project is supported by a grant from the Swedish
research Council (VR).
The applicant will join the lab of Dr. Martin Lind, and be part of the
well-equipped nematode lab, at the moment led by three PIs (Dr. Lind, Dr.
Bolund, Dr. Maklakov) interested in life-history evolution, inheritance, ageing
and sexual selection.
Qualifications: A relevant master degree or equivalent in evolutionary biology,
genetics, ecology or a related field. We are looking for you who are motivated,
highly reliable, driven and well-organised, and have a broad interest in
evolutionary biology. It is desirable if you have experience of laboratory work
and/or animal husbandry (of any organism). Because the holder of this position
will interact closely with other lab members, we put emphasis on personal
ability, independence and ability to collaborate. You should have the capacity
to express yourself well in speech and writing in English.
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POSITION 2: Causes and Consequences of Variation in Mutation Rate
Variation in mutation rate is a pivotal determinant of rates of adaptation and
extinction and a causative agent in human health problems, including ageing,
cancer, and genetic disease. Mutation rate has typically been treated as an
invariable species-specific parameter but this view has recently been
challenged by studies showing that mutation rate can vary with health,
nutritional state, sex, and age. The evolutionary causes and consequences of
this variation remain largely unexplored and the successful applicant will take
an experimental approach to understand among-individual variation in mutation
rate with the overarching aim to explore how this variation may influence
evolution in novel environments.
The research will take advantage of the finished genome assembly of the seed
beetle Callosobruchus maculatus, potentially combined with experiments on other
available laboratory study systems such as butterflies, fruit flies and
nematode worms. The successful candidate will employ experimental evolution
and/or mutation accumulation approaches in combination with comparative
analysis of quantitative genetic and genomic data.
The candidate will work in direct association with one PI (Dr. David Berger,
main supervisor) and share lab space with members of Prof. Göran Arnqvist’s
group, with whom interactions and collaborations are encouraged. Currently, the
beetle lab consists of 10 members working on various aspects of life history
evolution, sexual selection, and evolutionary genetics. The position is funded
by the Swedish Research Council (VR).
Qualifications: We seek a highly motivated and enthusiastic person with a broad
interest in evolutionary biology. Experience in
quantitative/molecular/population genetics, or in life history- and sexual
selection theory, is an advantage, but not a requirement. Experience of
laboratory work or in using statistical software (e.g. R, SAS, Mathematica,
Python) is also a merit. Because the holder of this position will interact
closely with other lab members, we will put emphasis on both independence and
ability to collaborate. The applicant is expected to be fluent in English.
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THE INFORMATION BELOW ALLPIES TO BOTH POSITIONS
WORKING PLACE: EBC hosts one of the world’s largest aggregations of
evolutionary biologists. The Department of Ecology and Genetics is an
international environment with staff and students from all over the world. Our
research spans from evolutionary ecology and genetics to studies of ecosystems.
A number of high-profile projects address natural and sexual selection, local
adaptation, speciation, molecular evolution, microbial diversity, and ecosystem
processes. For more information, see ieg.uu.se<http://ieg.uu.se>. Our graduate
school offers a creative and stimulating environment and offers a rich variety
of seminars, journal clubs, courses and possibilities to interact with other
scholars and students. Uppsala University is the oldest university in
Scandinavia and the city of Uppsala is a vibrant college town with beautiful
surroundings conveniently situated 40 minutes by train from Stockholm.
POSITION: The graduate program covers four years of full-time study. The
position can be combined with teaching (maximum 20%), which prolongs the
employment with the corresponding time. The successful candidate will receive
salary and full social benefits according to local agreements. More information
about salary levels:
http://www.saco.fackorg.uu.se/verksamhet/doktorandfragor/doktorandstege
Rules governing PhD candidates are set out in the Higher Education Ordinance
Chapter 5, §§ 1-7 and in Uppsala university's rules and guidelines
http://regler.uu.se/Rules_and_regulations_in_English/. More information about ;
postgraduate studies at Uppsala University is available at
http://www.teknat.uu.se/education/postgraduate/.
APPLICATION: The application should include 1) a letter of intent describing
yourself, your research interests and motivation for why you apply for the
current position and want to do a PhD, 2) a CV 3), a short description of your
education, 4) an authorized copy of your master degree and course grades, 5)
the names and email of at least two referees, 6) relevant publications
including master thesis. The application should be written in English.
Uppsala University aims for gender balance and diversity in all activities in
order to achieve a higher quality at all levels of the organization. We
therefore welcome applicants of any gender and with different birth background,
functionality and life experience.
PAY: According to local agreements
STARTING: As soon as possible or as otherwise agreed.
WORKING HOURS: 100 %
For further information about the two positions please contact:
Dr. Martin Lind, martin.lind@xxxxxxxxx<mailto:martin.lind@xxxxxxxxx> (Position
1)
http://www.martinlind.org/
Dr. David Berger, david.berger@xxxxxxxxx<mailto:david.berger@xxxxxxxxx>
(Position 2)
http://www.ieg.uu.se/animal-ecology/Research+groups/berger-lab/berger-research/
You are welcome to submit your application(s) no later than 15th of March 2017
Position 1: http://www.uu.se/en/about-uu/join-us/details/?positionId=134442
Position 2: http://www.uu.se/en/about-uu/join-us/details/?positionId=134561
You can apply for both positions, with separate applications.
—
Martin Lind
Assistant Professor
Dept. of Animal Ecology
Evolutionary Biology Centre
Uppsala University
Norbyvägen 18D
752 36 Uppsala
Sweden
http://www.martinlind.org/
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