Hi: If you used the Task Manager to close programs, it is important to close that as well. Also, if the Status menu is open, it will produce that message. If that doesn't help, try rebooting, resetting and/or reflashing. Pamela Rader, TECHNICAL SUPPORT American Printing House For The Blind 1839 Frankfort Ave. Louisville, KY 40206 PHONE: 1-800-223-1839, Ext. 307 >>> musicproandy@xxxxxxxxx 01/08/08 09:44PM >>> Hi. I go into disk drive and it says the hard drive is in use by other programs and to close out anything using the hard drive. What? I have no bloody programs open...