Hello. I wrote a while ago about an Exchange 2000 server problem with spam. I explained that it is open relay disabled, that the server has Mcafee SpamKiller installed and Mcafee VirusScan Enterprise v7.0 . Some of you told me (and I want to thank you all again for your answers) that it could be internal virus problem, AD password problems, etc. All of the internal computer have AV software installed (up to date), same with the servers. The AD password policy was changed some weeks ago (they are now strong passwords). And I have done all the tests (that i know) about open relay in exchange server. The problem is that the SMTP queue list doesn't stop to grow, and this weekend our domain as been listed in a ORL. The causes for the blacklist were to e-mails that my server sent to unautherized domains (not from, and to, our domain). Now I ask, how can it be possible? Is there anything that is missing me?? Please help me... I'm losing my hope that one day I will solve this problem. The network is secured by a Nokia firewall, E-Trust software and an ISA Server. Could it be something in the ISA Server? Thank you all. Best regards, António Vasconcelos.