89 scientists join call for EU action on hormone-disrupting chemicals <http://euractiv.us1.list-manage1.com/track/click?u=8f42af8d26b382b0bcc4930b2&id=238f904719&e=7e023b6757> Rising levels of cancer along with increasing brain, thyroid and reproductive problems have led an international group of scientists to call for tougher EU regulation on some chemicals used in everyday life. EFSA paves way for regulating endocrine disruptors in food <http://euractiv.us1.list-manage1.com/track/click?u=8f42af8d26b382b0bcc4930b2&id=e8585a250d&e=ce3de1deae> The European Food Safety Authority (EFSA) has endorsed the World Health Organization's (WHO) definition of endocrine disruptors, paving the way for the European Commission to regulate those chemicals in food. The pesticide industry reacted angrily, saying the scientific process has been "rushed to meet political deadlines". Chipping away at animal testing<http://bostonherald.com/business/healthcare/2013/03/chipping_away_at_animal_testing> Harvard University researchers are tapping into Sony's manufacturing expertise with the goal of mass-producing matchbox-sized "organs-on-chips" that could make it possible for scientists to test new drugs easily without animal trials. Best Practices for Establishing and Maintaining Mammalian Cell Culture<http://www.biocompare.com/Editorial-Articles/133332-Best-Practices-for-Establishing-and-Maintaining-Mammalian-Cell-Culture/?goback=%2Egde_127075_member_225447384> Cell-culture tools and expertise abound today, and it has never been a better time to learn the tricks of the trade. Perhaps you've helped with maintaining cultures, but now you'd like to start your own. Here are some main considerations to keep in mind when setting up your own cultures. Industry evidence sets animal welfare benchmark for short-term toxicity studies<http://www.nc3rs.org.uk/news.asp?id=1932> The maximum-tolerated dose of a drug candidate can be determined in short-term toxicity studies without exceeding a bodyweight loss of 10 per cent in rats and dogs, according to a review by 15 pharmaceutical companies and contract research organisations published in Regulatory Toxicology and Pharmacology. Test your knowledge on the new hazard pictograms in your language ECHA's online quiz on the new hazard pictograms is now available in 22 EU languages. Take the test to make sure you know them, you can read the labels and stay safe. More <http://fceg.espsrv.com/f/tr.aspx/?&x=pv&6Uh&h=uy1/z-0d&x=pv&=utszjib=0ikf_qs05:757jiec560hq9bc2hk&oNCLM> Grouping of substances and read-across<http://echa.europa.eu/web/guest/support/grouping-of-substances-and-read-across> ECHA has developed an illustrative example of a grouping of substances and read-across approach to support companies to comply with their obligations under REACH. You can also inform or consult the ESTIV membership by sending your mail to: estiv@xxxxxxxxxxxxx<mailto:estiv@xxxxxxxxxxxxx> Please join the ESTIV group on LinkedIn so others can contact you directly and are immediately updated when you change address and/or position. Jan van der Valk, PhD ESTIV list owner 3Rs-Centre Utrecht Life Sciences, and NKCA Dept. Animals in Science and Society Fac. Veterinary Medicine Email: J.vanderValk@xxxxx<mailto:J.vanderValk@xxxxx>