New complimentary webinar from Science share with your science teachers!
A high-resolution look at the human cell: Introducing the Human Cell Atlas
You are invited to hear our panel of experts on March 8, 2017, in this live,
online educational seminar. For more information and complimentary
registration visit: webinar.sciencemag.org
<http://click.aaas.sciencepubs.org/?qs=387cf9dd2141d673a02eed3f3034304490e1d
5e78a0d26b5f1ce869e427764f8022a0bfaa4abaf4acdae00d42980ac685be6302ea4d439ce>
Date: Wednesday, March 8, 2017
Time: 12 noon Eastern, 9 a.m. Pacific, 5 p.m. UK, 6 p.m. Central Europe
Duration: 1 hour
<http://click.aaas.sciencepubs.org/?qs=387cf9dd2141d67399e0f4347bc96cb1eab6a
28c0021adfdf98f30a28752f70b0b36e92e06b30d5e0081597f55580ccfcef22760c2f56d54>
About This Webinar
Resolving the spatial distribution of the human proteome at a subcellular
level greatly increases our understanding of human biology and disease. A
high-resolution map of the human cell has been generated-part of the Human
Protein Atlas database-that provides the in situ localization of 12,036
human proteins at a single-cell level, covering 30 subcellular structures,
and enabling 14 major organelle proteomes to be defined. The high spatial
resolution of the data has allowed the identification of novel protein
components in all major organelles, as well as the characterization of fine
cellular structures such as the cytokinetic bridge and nuclear bodies. An
integrative approach to data generation includes strict validation criteria
using gene silencing, paired antibodies, and fluorescently tagged proteins.
The Cell Atlas reveals that approximately half of all proteins localize to
multiple compartments and that many proteins show cell-to-cell variation in
terms of protein abundance or spatial distribution. In this webinar, we will
introduce the new Human Cell Atlas, outlining how it is being used to define
the spatiotemporal organization of the human proteome at a subcellular
level.
During the webinar, the viewers will learn about:
The generation of the Human Cell Atlas and how its data was validated
The process for identification and characterization of the organelle
proteomes
The identification and localization of proteins, particularly those
showing complex distribution and cell-to-cell variations in expression.
The speakers will be available to answer your question live during the
broadcast!
Participants:
Mathias Uhlén, Ph.D.
KTH Royal Institute of Technology
Stockholm, Sweden
Emma Lundberg, Ph.D.
KTH Royal Institute of Technology
Stockholm, Sweden
Register at:
<http://click.aaas.sciencepubs.org/?qs=387cf9dd2141d673a02eed3f3034304490e1d
5e78a0d26b5f1ce869e427764f8022a0bfaa4abaf4acdae00d42980ac685be6302ea4d439ce>
webinar.sciencemag.org
Questions? E-mail: webinar@xxxxxxxx <mailto:webinar@xxxxxxxx> .
Produced by the Science/AAAS Custom Publishing Office and sponsored by Atlas
Antibodies.
best,
debbie
Debbie Abilock
<https://prezi.com/tftyaf7wjmds/debbie-abilock-adding-friction/> Adding
Friction, a column @SLC
Jane Jacobs was forever taking on ambitious subjects from new directions,
marching imperturbably into all she didnt know. Shed never understand,
she told an interviewer once, how other authors could stand the boredom of
just writing down everything [they] already knew. But she paid the price
for indulging her insatiable curiosity. With each new book... I always get
scared to death. Caught up in complexities of a new field not at first
fully apparent, I realize its too deep for me, but I have to keep on with
it. Until she gets it.
- from Eyes on the Street: The Life of Jane Jacobs by Robert Kanigel;
Knopf, 2016 p. 322.
