http://www.gpo.gov/fdsys/pkg/FR-2012-04-13/html/2012-8942.htm SUMMARY: The multiagency Tox21 Initiative aims to improve hazard assessment of compounds potentially harmful to humans and the environment. This will be accomplished through the use of integrated high throughput screens that provide information on the ability of a substance to perturb biological pathways related to toxicity. On behalf of the Tox21 Consortium and its Assays and Pathways Working Group, the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) is accepting nominations for HTS biochemical- or cell-based assays. Assays selected for further evaluation and found to be compatible with the HTS program will support Tox21 by providing data on endpoints that serve as markers for initiating or downstream events in toxicity pathways. DATES: The nomination of HTS assays to Tox21 is an ongoing process and will continue to remain open. Periodic updates to this notice may be posted to reflect new focus areas of the Tox21 HTS program. FOR FURTHER INFORMATION CONTACT: Nominations of assays should be submitted online at http://iccvam.niehs.nih.gov/contact/Tox21-nomination.htm (preferred means) or to Dr. Warren Casey, Deputy Director, NICEATM, NIEHS, P.O. Box 12233, Mail Stop: K2-16, Research Triangle Park, NC 27709, (telephone) 919-541-2384, (fax) 919-541-0947, (email) niceatm@xxxxxxxxxxxxx<mailto:niceatm@xxxxxxxxxxxxx>. Courier address: NICEATM, NIEHS, Room 2034, 530 Davis Drive, Morrisville, NC 27560. Kristie Sullivan, MPH Secretary American Society for Cellular and Computational Toxicology www.ascctox.org<http://www.ascctox.org>