NEWS> Lancet Publishes and Article Discussing the Cause of Severe Acute Respiratory Syndrome (SARS)
- From: Gleason Sackmann <gleason@xxxxxxxxxxxxxxx>
- To: NetHappenings <nethappenings@xxxxxxxxxxxxx>
- Date: Thu, 10 Apr 2003 09:00:00 -0500
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Net Happenings - From Educational CyberPlayGround
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Date: Wed, 9 Apr 2003 17:24:04 -0400 (EDT)
From: "David P. Dillard" <jwne@xxxxxxxxxxxxxxxxxxxxx>
ARTICLE: Lancet Publishes and Article Discussing the Cause of Severe Acute
Respiratory Syndrome (SARS)
Lancet
Volume 361, Number 9364 05 April 2003
Coronavirus as a possible cause of severe acute respiratory syndrome
J S M Peiris, S T Lai, L L M Poon, Y Guan, L Y C Yam, W Lim, J Nicholls, W
K S Yee, W W Yan, M T Cheung, V C C Cheng, K H Chan, D N C Tsang, R W H
Yung, T K Ng, K Y Yuen, and members of the SARS study group
Summary
Background An outbreak of severe acute respiratory syndrome (SARS) has
been reported in Hong Kong. We investigated the viral cause and clinical
presentation among 50 patients.
<http://www.thelancet.com/journal/journal.isa>
Background An outbreak of severe acute respiratory syndrome (SARS) has
been reported in Hong Kong. We investigated the viral cause and clinical
presentation among 50 patients.
<snip>
Findings Patients' age ranged from 23 to 74 years. Fever, chills, myalgia,
and cough were the most frequent complaints. When compared with chest
radiographic changes, respiratory symptoms and auscultatory findings were
disproportionally mild. Patients who were household contacts of other
infected people, and had older age, lymphopenia, and liver dysfunction
were associated with severe disease. A virus belonging to the family
Coronaviridae was isolated from two patients. By use of serological and
reverse-transcriptase PCR specific for this virus, 45 of 50 patients with
SARS, but no controls, had evidence of infection with this virus.
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