publishig mdaemon behind isaserver

Hi folks:
I have published my mail server (mdaemon) behind isa server with secure mail 
server wizard.But it doesn't work.
The result of entering the valid ip of isa server that i have published mdaemon 
on it on IE is "The page cannot be displayed".
mail server is securenat client for isa server.
Should I make any other configuraton?

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