Good Afternoon, I'm trying to get my Exchange 5.5 Server to play nice with my newly installed ISA 2000 (SE) Server. I had an eval copy of ISA installed and configured previously and it was working flawlessly with Exchange. Since the change I am unable to send e-mail from my Exchange server. I can receive SMTP and POP3 mail no problem. I ran the Secure Mail setup wizard and I setup a protocol rule for DNS zone tansfer and query server. There is also the SMTP rule that was created by the wizard. I remember coming across an article on isaserver.org with step by step instructions on how to do this which I can't find again. Can someone point me in the right direction, I'm obviously missing something. TIA, Scott.