The National Institute of Environmental Health Sciences (NIEHS) is offering grants to support development of novel assays by U.S. small business concerns. The deadline for applying for these grants has been extended to February 19. The grants will support development of medium- to high-throughput assays to evaluate the effects of toxicants on pluripotent or induced pluripotent cells with respect to cell differentiation and the resulting differentiated cell populations. Assays will provide information on mechanisms of chemically induced biological activity, help to prioritize chemicals for more extensive toxicological evaluation, support more predictive models of in vivo biological response, and potentially inform the role of genetic diversity in toxicological effects. R41 grants (Phase 1) will award up to $225,000 for up to one year; R43/R44 grants (Phase 1, Phase 2, Fast-Track) will award up to $225,000 for up to one year for Phase 1 applications and $1,500,000 for up to two years for Phase 2 applications. Additional information is available at R41: http://grants2.nih.gov/grants/guide/rfa-files/RFA-ES-15-005.html R43/R44: http://grants2.nih.gov/grants/guide/rfa-files/RFA-ES-15-006.html