[ SHOWGSD-L ] Re: Something that definitely should be considered in regards to DM
- From: Ken Tank <tanksr@xxxxxxxxx>
- To: showgsd gsd <Showgsd-l@xxxxxxxxxxxxx>
- Date: Wed, 23 May 2012 17:36:31 -0700
I don't believe there is enough evidence to show the test is accurate
especially in GSDs. It is my understanding that they could not replicate
their results in GSDs, maybe they could in other breeds I don't know.
Also, there are no long term generational studies.
So, at this point, it is still research and not a viable tool for us. Dr.
Gerald Bell states "Breeds susceptible to DM should not have their mating
choices altered due to carrier or homozygous (at risk) status of DM unless
there is knowledge of close (first or second generation) relatives
diagnosed with DM." The only way to positively diagnose DM is by necropsy
as there are many other problems/diseases that mimic DM.
IMHO they should be testing dogs at no charge (or certainly a lot less than
$65??) until they have a viable test and long term, generational studies.
Only then should they make claims of whether a dog will be affected or pass
on the gene. As it is right now, the test really tells us nothing.
Keep in mind that the University of Missouri (Dr. Coates employer) owns the
patent to this test so do your homework and check other resources, there
are many dissenting opinions.
As one of my military friends says "Trust, but verify".
Ken
On Wed, May 23, 2012 at 2:59 PM, David Fritsche <d_fritsche@xxxxxxxxxx>wrote:
>
> DM is still such a controversial disease that has many bewildered. They say
> the test is accurate but I do ask where is all the research statistics that
> prove the accuracy. I have a male who tested at risk and go back and forth
> on what I should do. Information like in the following link really makes me
> question the current tests. Would love to hear other opinions and thoughts
> on the subject. Keep it friendly ;)
>
> http://www.change.org/petitions/ofa-university-of-missouri-dna-dm-test-desig
> nations
>
>
> --------------------------------------------------------------------------------
>
> Hi Tammy;
> I read the petition and the notes from those who are supporting it and I
> suspect that this is simply more of the ongoing controversy that started
> when U of Missouri and Dr. Coates published their findings. In order for a
> university team, such as the one at U of Mi. to publish their findings they
> have to prove their hypothesis to their peers and have a repeat of the
> process that provided the findings. Then they can publish. The controversy
> broke out when the hypothesis of their theoretical opposition could not
> replicate nor prove their findings. So, the bulk of hard science has fallen
> in line with the U of Missouri findings. That does not mean that hard
> science does not ever make a mistake, nor does it mean that allegorical and
> experiential evidence should always be discarded. But there are many of us,
> who all too often are willing to follow those who make a case without
> research in contrast to those who have done the work.
>
> I have dear friends who swear that the OFA U of M tests are worthless, but
> cannot show where the findings of the university team are in error. That is
> simply because, in some cases, they have wonderful dogs who come from DM
> lines and they do not want to throw them away. They shouldn't. Even if a
> dog
> is a carrier, OFA recommends that the results of the test be used as a
> breeding tool and not be the only item considered in a breeding decision.
> Should you or I breed a dog with one DM marker? Difficult decision! But
> before the test, we all bred what we had without knowing and look where it
> got us. And, in many cases, many breeders still breed without doing the
> test
> trusting that, since they have not had it in their lines in the past, they
> are free from it. Could well be.
>
> So you raise a difficult question. The answer is probably as individual as
> anyone one of us on the list. We have decided to do the test, and have
> found
> two dogs who are not at risk but who are carriers. We have not bred them to
> date, and probably won't, but I cry inside ever time I see my boy move
> across the yard. Probably the best moving dog I have ever seen. Bu my
> question for myself is, do I want to pass on his strengths along with his
> weaknesses. My answer is, so far, no; but gosh am I tempted.
>
> Many disagree with me, and they have reasons for their position.
> I will change mine, when I see better science. For me, it is not a
> controversial disease, even though I suffer from that conclusion.
> Dave
>
>
>
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