.
.
MEDICAL: DISEASES: ZIKA VIRUS :
MEDICAL RESEARCH:
Newly Discovered Antibody Neutralizes Zika Virus, Shows Mouse Study
.
.
Newly Discovered Antibody Neutralizes Zika Virus, Shows Mouse Study
Nov 11, 2016
A research team led by Vanderbilt University Medical Center scientist
Prof. James Crowe, Jr., has isolated a human monoclonal antibody that in a
mouse model markedly reduced infection by the Zika virus.
Sci-News
http://www.sci-news.com/medicine/
antibody-neutralizes-zika-virus-04356.html
.
A shorter URL for the above link:
.
http://tinyurl.com/gvvoqk7
.
.
Zika virus is a member of the Flavivirus genus in the Flaviviridae family.
It was accidentally discovered in Uganda in 1947, during a course of
surveillance on mosquitoes and primates.
.
Since a major outbreak was reported in Brazil last year, Zika infections
have been reported throughout Africa, Asia, the Pacific, and the Americas.
.
During the past 15 years, Prof. Crowe and his colleagues have developed a
high-efficiency method for isolating human monoclonal antibodies that has
enabled to them identify neutralizing antibodies against a wide range of
viral infections, from Ebola to HIV.
.
Monoclonal antibodies are made from a single clone of B cells, a type of
white blood cell, that have been fused to myeloma cells to form
fast-growing hybridomas. This allows scientists to quickly generate large
quantities of antibodies against specific viral targets.
.
In the current study, Prof. Crowe and co-authors from the Vanderbilt
University Medical Center and the Washington University School of Medicine
isolated 29 antibodies from the blood of three patients who had recovered
from Zika infection. The antibodies reacted to the envelope or E protein
on the surface of the virus.
.
In cell culture studies, the team identified one, called ZIKV-117, that
efficiently neutralized in the lab five Zika strains corresponding to
African, Asian, and American lineages.
.
Male mice that received a single dose of ZIKV-117 even five days after
Zika infection were more likely to survive than those given a control
antibody, suggesting that the antibody could treat active Zika infection.
.
The scientists next found that ZIKV-117 had protective effects during
pregnancy.
.
Pregnant mice that received the antibody and were then infected with Zika
virus had lower levels of the virus in their blood and brain tissues than
mice not treated with ZIKV-117.
.
Among the treated mice, the team found protective levels of ZIKV-117 in
fetal tissues and markedly reduced levels of virus in the placenta and the
fetal brain
.
.
The complete article may be read at the URL above.
.
.
Sincerely,
David Dillard
Temple University
(215) 204 - 4584
jwne@xxxxxxxxxx
http://workface.com/e/daviddillard
Net-Gold
https://groups.io/g/Net-Gold
http://groups.yahoo.com/group/net-gold
http://listserv.temple.edu/archives/net-gold.html
https://groups.io/org/groupsio/Net-Gold/archives
http://net-gold.3172864.n2.nabble.com/
Temple University and Google Sites Research Guides
AND Discussion Group Directory
http://tinyurl.com/ngda2hk
OR
https://sites.google.com/site/researchguidesonsites/
RESEARCH PAPER WRITING
http://guides.temple.edu/research-papers
EMPLOYMENT
http://guides.temple.edu/employment-guide
INTERNSHIPS
http://guides.temple.edu/employment-internships
HOSPITALITY
http://guides.temple.edu/hospitality-guide
DISABILITIES AND EMPLOYMENT
http://guides.temple.edu/c.php?g=134557
INDOOR GARDENING
https://groups.io/g/indoor-gardening
Educator-Gold
http://groups.yahoo.com/group/Educator-Gold/
K12ADMINLIFE
http://groups.yahoo.com/group/K12AdminLIFE/
PUBLIC HEALTH RESOURCES INCLUDING EBOLA
http://guides.temple.edu/public-health-guide
STATISTICS SOURCES RESEARCH GUIDE
http://guides.temple.edu/statistics-sources
Social Work and Social Issues Discussion Group
https://groups.io/g/social-work
Tourism Discussion Group
https://groups.io/g/Tourism
Digital Scholarship Discussion Group
https://groups.io/g/DigitalScholarship/threads
https://listserv.temple.edu/cgi-bin/wa?A0=DIGITAL-SCHOLARSHIP
https://groups.yahoo.com/neo/groups/digital-scholarship/info
https://digitalscholarshipandscholarlypublication.wordpress.com/
Copyright Research Guide
Copyright, Intellectual Property and Plagiarism Sources
http://guides.temple.edu/copyright-plagiarism
Fair Use
http://guides.temple.edu/fair-use
Blog
https://educatorgold.wordpress.com/
Articles by David Dillard
https://sites.google.com/site/daviddillardsarticles/
Information Literacy (Russell Conwell Guide)
http://tinyurl.com/78a4shn
Nina Dillard's Photographs on Net-Gold
http://www.flickr.com/photos/neemers/
Twitter: davidpdillard
Temple University Site Map
https://sites.google.com/site/templeunivsitemap/home
Bushell, R. & Sheldon, P. (eds),
Wellness and Tourism: Mind, Body, Spirit,
Place, New York: Cognizant Communication Books.
Wellness Tourism: Bibliographic and Webliographic Essay
David P. Dillard
http://tinyurl.com/o4pn4o9
Rail Transportation
https://groups.io/org/groupsio/RailTransportation
INDOOR GARDENING
Improve Your Chances for Indoor Gardening Success
http://tech.groups.yahoo.com/group/IndoorGardeningUrban/
SPORT-MED
https://www.jiscmail.ac.uk/lists/sport-med.html
http://groups.yahoo.com/group/sports-med/
http://listserv.temple.edu/archives/sport-med.html
HEALTH DIET FITNESS RECREATION SPORTS TOURISM
https://groups.yahoo.com/neo/groups/healthrecsport/info
http://listserv.temple.edu/archives/health-recreation-sports-tourism.html
.
.
Please Ignore All Links to JIGLU
in search results for Net-Gold and related lists.
The Net-Gold relationship with JIGLU has
been terminated by JIGLU and these are dead links.
http://groups.yahoo.com/group/Net-Gold/message/30664
http://health.groups.yahoo.com/group/healthrecsport/message/145
Temple University Listserv Alert :
Years 2009 and 2010 Eliminated from Archives
https://sites.google.com/site/templeuniversitylistservalert/
.
.
