[mira_talk] Re: assembling variants

  • From: Bastien Chevreux <bach@xxxxxxxxxxxx>
  • To: mira_talk@xxxxxxxxxxxxx
  • Date: Thu, 4 Mar 2010 18:04:14 +0100

On Donnerstag 04 März 2010 Alexie Papanicolaou wrote:
> my two cents:
> One option would be to map your reads to the reference consensus
> (created by MIRA) using a program like maq/bowtie (one strain at a
> time).

I think the problem was she doesn't have them separated, but rather as a 
mixture.

I don't know about maq/bowtie, but I think they don't handle large 
discrepancies (inserts / deletions) more than a couple of bases very well. 
With MIRA you might get those and even if not, it will set a whole armada of 
tags pointing to that problematic site.

Regards,
  Bastien

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