[estiv] FW: IVTS - Vacancy Update

From: "Valk, J.B.F. van der (Jan)" <j.vandervalk@xxxxx>
To: "'estiv@xxxxxxxxxxxxx' (estiv@xxxxxxxxxxxxx)" <estiv@xxxxxxxxxxxxx>
Date: Mon, 14 Apr 2014 07:29:50 +0000

[Immagine rimossa dal mittente. IVTS]

IVTS - Vacancy Update

Senior Scientist Genetic Toxicology
AstraZeneca
Cambridge

Closing date 21 April

Within the overall AstraZeneca strategy, cutting-edge innovation is at the
heart of what we do, and our R&D strategy has been carefully constructed to
deliver on our promise to our patients, customers, and shareholders.

Description of the department and role
Discovery Safety is new department within Drug Safety and Metabolism and
applies cutting edge molecular, cellular and in vivo techniques to assist in
the discovery of new and effective medicines.

The Discovery Safety group provides broad project support starting with target
identification up to candidate nomination for start of dose range finder
toxicology conducted by our regulatory safety department. The Discovery Safety
group includes a dedicated team of scientists who work closely with the local
disease areas, in silico experts for safety and ADME, genetic toxicology
expertise and secondary pharmacology combined with early assay development.

We’ll look to you to bring in new techniques and ideas in early clinical phases
by identifying molecules with the “Right Safety” profile. The role will be
mainly laboratory based & conduct genetic toxicology studies and understand the
practices, principles and concepts associated with reviewing, planning,
conducting, validating, reporting a variety of studies.

The role will also be to keep abreast of new science and techniques and assess
their potential use in genetic toxicology.

The role may where necessary, understand and apply Home Office Regulations and
ensure the welfare and environment of laboratory animals is maintained
consistent with scientific objectives.

Accountabilities/Responsibilities
You will:

• Have an understanding of how genetic toxicology interacts with others within
the discovery safety and how they support the objectives of the business.

• Maintain a knowledge internally and externally of new trends in study design,
experimental techniques and specialised equipment.

• Contribute to the objectives of the department through active participation
in department and cross functional project teams.

• Have expertise in planning and organising daily work, and perhaps that of
team members. The role holder will evaluate the progress of own work, and
perhaps those of other team members, using judgement to recognise anomalous
performance or results.

• Understand need for on-going change and will assist others in handling
associated uncertainty.

Minimum Requirements - Education and Experience

Essential

• Will possess at least a biological sciences or chemistry BSc or higher degree
and preferably have relevant laboratory experience of conducting safety
assessment or other laboratory studies.

Desirable

• Knowledge of Ames, in vitro and in vivo Micronucleus tests would be helpful,
though training can be given.

• Excellent written and verbal communication skills.

• Cell culture experience and sterile technique and microscopy particularly
fluorescent would
be an advantage.

For further information please contact
Ann.Doherty@xxxxxxxxxxxxxxx<mailto:Ann.Doherty@xxxxxxxxxxxxxxx?subject=Senior%20Scientist%20-%20Genetic%20Toxicology>

Full application via the AZ website below

http://jobs.astrazeneca.com/jobs/details/l1rRD912-senior-scientist-genetic-toxicology<http://ivts.createsend4.com/t/y-l-iliykrt-ctkhhjjid-j/>

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[estiv] FW: IVTS - Vacancy Update

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