[ SHOWGSD-L ] Re: warning on COMFORTIS - new Heartworm preventative
- From: "Kristen Cabe" <showgsdlist@xxxxxxxxx>
- To: SHOWGSD-L <showgsd-l@xxxxxxxxxxxxx>
- Date: Wed, 25 Jun 2008 14:19:46 -0400
Comfortis is actually a flea control medication, NOT a heartworm
preventative. The problem is when Comfortis is given to dogs who are taking
high doses of ivermectin as well.
Kristen
On Wed, Jun 25, 2008 at 9:40 AM, Peggy <pmick12@xxxxxxxxxxx> wrote:
> This was in my inbox this morning:
> For everyone's info.....
>
>
>
>
> FDA, Center for Veterinary Medicine
> June 24, 2008
> COMFORTIS(R) and ivermectin interaction Safety Warning Notification
> Today the U.S. Food and Drug Administration (FDA) Center for Veterinary
> Medicine (CVM) is announcing that it has received reports of adverse
> reactions in dogs receiving the drug Comfortis(R) (spinosad) concurrently
> with
> high, extra-label doses of the drug ivermectin. The clinical signs of these
> adverse reactions are consistent with ivermectin toxicity.
> Comfortis(R) (spinosad), manufactured by Elanco Animal Health, a division of
> Eli Lilly and Company, is a monthly oral, chewable tablet used for the
> prevention and treatment of flea infestations on dogs. Veterinarians who
> use
> high, extra-label doses of ivermectin to treat dogs with non-responsive
> demodectic mange and other conditions should be aware that some dogs have
> developed signs of ivermectin toxicity when ivermectin is used concurrently
> with Comfortis(R) (spinosad).
> CVM and Elanco Animal Health are advising veterinarians that dogs receiving
> extra-label doses of ivermectin should not receive concurrent treatment
> with
> Comfortis(R) (spinosad).
> CVM is working with Elanco Animal Health as they address this issue.
> Additional information regarding this safety warning can be obtained on the
> Elanco Animal Health website.
> Lilly Companion Animal Health Technical Bulletin: Spinosad and the
> Extra-Label Use of High Dose Ivermectin for the Treatment of Generalized
> Demodicosis in Dogs - http://elms.xh1.lilly.com/10788_03_tech_Bulletin.pdf
>
>
>
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--
Let the trainer examine himself when the dog makes a mistake, or does not
understand the exercise, or fails in obedience, and let him ask "Where am I
at fault?" -- Capt. Max von Stephanitz
http://www.pedigreedatabase.com/gsd/pedigree/520408.html -Deja vom Ausland
BH
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POST is Copyrighted 2007. All material remains the property of the original
author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind
are permitted without prior permission of the original author AND of the
Showgsd-l Management. ALL RIGHTS RESERVED.
ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY
MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS
PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY
FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE
PROSECUTED.
For assistance, please contact the List Management at admin@xxxxxxxxxxxx
VISIT OUR WEBSITE - www.showgsd.org
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