Has your vet suggested doing a necropsy on one of the puppies? Have you ruled out Herpes? Has the Mom's milk been tested? We had a similar think happen to us with our ROM bitch with several litters, not just one. Babies were born, healthy, vibrant, then one by one they faded on me. One vet told me is was Herpes. I said no, it was not. We did test Mom and she came back negative, so that ruled out Herpes. To make a long story short, it turned out to be an E coli infection. Mom had it and babies were all fine until they passed thru the birth cannel. They, one by one, died. We tried everything. Necropsies would come back with no findings. We tried treating Mom for E coli "before" she had her puppies so that when she gave birth, they would be ok. Sounded like a great plan, however, it did not work, her E coli infection was resistant to the drug she was treated with. (and yes we did a sensitivity panel and the infection was supposed to be sensitive to this drug) Her last litter she had 7, we were down to 3 with no answers. I called Scottie Sherlock and she told me to do a very radical treatment. To give the babies indictable Baytril (if I could talk my vet into it) for 3 days. I told my vet what she had said and since he had no other answers and could not save the babies, I got the Baytril. We saved 2 out of the 3 babies. One of those babies that made it is, Ch. JaDon's Weekend Rendezvous. One note to this. I have seen E coli on some of our cultures before doing breedings on other bitches, but Haley's was unique. It was resistant to most drugs. One follow up on this sad story, is that none of her progeny had this problem. It was unique to Haley. I hope you can save your remaining babies. Good luck. Janet Good luck with the remaining babies. ============================================================================ POST is Copyrighted 2006. All material remains the property of the original author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind are permitted without prior permission of the original author AND of the Showgsd-l Management. ALL RIGHTS RESERVED. ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE PROSECUTED. For assistance, please contact the List Management at admin@xxxxxxxxxxxx VISIT OUR WEBSITE - URL temporarily deleted due to AOL issues ============================================================================