Hi Today I was thinking about what Terry as well as other friends had said about exposure, and its possible relation to Mega, and the xrays which showed several of my pups esophagus not working properly, and being diagnosed with megaesophagus. It hit me today my girl had been on Doxi up until the day before she was bred and now think this maybe this s related since my little boy seems so strong and has no issues where his older littermates seemed to be having issues, (He also did not open his eyes till day 17 so I know he was/is very young compared to his littermates) . Today I looked it up and found increased risk for cleft pallet (and I also did have a cleft pallet in this litter too which I have never had before either). retardation of skeletal development, alter growth, and is known to cause Esophagreal atresia which is when the esophagus does not devlop properly and other defects in animal and human studies where Doxi was administed during conception and/or first trimester of pregnancy I don;t know if this is related to what happend with my girl and her pups, it could be genetics, a bad mix, or maybe the meds without me realizing it at the time. It was/is definately very scary, and heartbreaking to say the least, and I just pray I will never see this ever again. http://www.1800petmeds.com/Doxycycline-prod10340.html http://www.toxbase.org/upload/Pregnancy%20pdfs/Doxycycline%202008.pdf http://www.merck.com/mmpe/print/lexicomp/doxycycline.html http://webcache.googleusercontent.com/search?qÊche:YgaCKLBt60EJ:www.drugs.com/pro/doxycycline.html+Doxycycline+pregnant+dog+breed&cd=5&hl=en&ct=clnk&gl=us http://www.drsfostersmith.com/product/prod_display.cfm?pcatid?38 Ann Marie www.amarigsd.com Home of Ch Fairway's Leah v Nadelwald TC ROM OFA Ch Amari's Beware of Foxy Roxy CGC TC OFA Amari's Elizabeth Taylor (Major pointed/Best in Show Bred-By winner) Breeder/Owner of R/Best in Futurity Ch Amari's Ava Gardner TC OFA Ch Amari's Bandit of Broadcreek OFA (Multiple Group Placer) Amari's Blissfull Jazz CGC TDI (Major pointed) Amari's Cinderella von Hornberger (Ch pointed) Amari's Chances Are (Ch pointed) Amari's Ella Enchanted (Ch pointed @ 7 months/Major Reserve @ 11 months) ============================================================================ POST is Copyrighted 2010. All material remains the property of the original author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind are permitted without prior permission of the original author AND of the Showgsd-l Management. ALL RIGHTS RESERVED. ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE PROSECUTED. For assistance, please contact the List Management at admin@xxxxxxxxxxx VISIT OUR WEBSITE - http://showgsd.org NATIONAL BLOG - http://gsdnational.blogspot.com/ ============================================================================