[ SHOWGSD-L ] Re: Hemangiosarcoma
- From: InquestGSD@xxxxxxx
- To: showgsd-l@xxxxxxxxxxxxx
- Date: Sat, 3 Jun 2006 21:21:45 EDT
From the National Canine Cancer Foundation:
Hemangiosarcoma
Canine hemangiosarcoma is an incurable tumor of cells that line blood vessels
(endothelial cells). Based on current estimates of the lifetime risk of
cancer in dogs and the prevalence of hemangiosarcoma, we predict that of the
73.9
million pet dogs living in the United States today, as many as two million
may get this cancer and die from it. Although dogs of any age and breed are
susceptible to hemangiosarcoma, it occurs more commonly in dogs beyond middle
age, and in breeds such as Golden Retrievers, German Shepherd Dogs, Portuguese
Water Dogs, and Skye Terriers, among others.
Hemangiosarcoma is extremely indolent â?? that is, it develops slowly and is
essentially painless â?? so clinical signs are usually not evident until the
advanced stages when the tumors are resistant to most treatments. Less than
50%
of dogs treated with standard-of-care of care for this tumor (surgery and
intensive chemotherapy) survive more than six months. Many dogs die from
severe
internal bleeding before there is an opportunity to institute treatment. For
this reason, our lab is working to develop a test for early detection, which
will allow us to diagnose the disease before it is clinically evident.
Similarly, a number of novel approaches using targeted therapies and tumor
vaccines to treat canine hemangiosarcoma are in preclinical development or in
the early stages of clinical testing.
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