Content-Type: text/plain; charset="US-ASCII" Content-Transfer-Encoding: 7bit I have used Frontline for years and reapply every 45 days with no problem. I had thought about switching to Bio-Spot but was never able to get an answer from the Mfg. concerning usage on a bitch in whelp, with Frontline, it states on the package; can be used on pregnant bitches. As for the dog getting wet .... Since Frontline works for me, I decided the extra money for preventing was worth more then trying to get rid of .... Lyn ~ Cherlyn Shepherds Where Intelligence and Conformation Come Together ============================================================================ POST is Copyrighted 2004. All material remains the property of the original author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind are permitted without prior permission of the original author AND of the Showgsd-l Management. ALL RIGHTS RESERVED. ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE PROSECUTED. For assistance, please contact the List Management at admin@xxxxxxxxxxxx VISIT OUR WEBSITE - http://www.showgsd.org ============================================================================