There are approximately 125 FREE BLOOD CARDS AVAILABLE, to those of you who wish to participate. They are looking for healthy dogs with no signs of any neurological conditions. The data will be totally private, with a few simple questions, however if you desire the info to be posted on OFA that option is available. Please contact me privately for further information . Morgan As of now, we want to sample only *Standard* GSDS from the USA, as that is what we have already sampled. Consistency in the research is very important, so as not to skew the results. If in the future, other GSD clubs around the world would like to chip in with research funds, we could easily expand our research. However, with the GSD Club financing this study, we need to test as many of our own dogs, here in the USA, as possible. From the samples we have been looking at, it appears that 19.6% (approximately) of GSD carry the change in the canine version of MHCII which puts them at risk of developing GSDM. That figure is much higher than we originally suspected :( People need to get serious about DM, realize it is a real problem in the breed and support the research. Failure to do so will be like asking for whom the bell tolls- it will be for our breed :( As far as breeding a dog with a positive DM marker- here is DR Clemmons position. " I do not advocate elimination of dogs with these changes from the gene pool, but it is one consideration for whether to use them in breeding. If they bring something else to the breed that no similar "negative" dog does not, then it would be a shame to loose their genetic potential. Working with their offspring should then be done to keep the good traits and eliminate any bad ones. However, that requires lots of thought and careful record keeping to achieve. I have always thought that breeders should decide what they want to achieve, categorize it, prioritize it and judge all matings based upon the ideal outcome. In that case, the presence of a "positive" would be a negative. Any animal that fell below some high measure of the ideal, would not be used in breeding. In that way, a flash test can still be part of rational breeding, just like deciding upon good teeth and temperament. Ultimately it is up to the breed to determine what to do. We are trying to make it so that people can make informed choices and to help diagnose and treat those who are ill. However, since we see a relationship to this genetics and the disease (in almost all cases), that does bring into question whether genetic testing is important. For the dog who gets GSDM and the owner of a dog who might get GSDM, it is certainly a concern. Dr Clemmons" . Yes, you may forward this message :) --------------------------------- TV dinner still cooling? Check out "Tonight's Picks" on Yahoo! TV. ============================================================================ POST is Copyrighted 2007. All material remains the property of the original author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind are permitted without prior permission of the original author AND of the Showgsd-l Management. ALL RIGHTS RESERVED. ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE PROSECUTED. For assistance, please contact the List Management at admin@xxxxxxxxxxxx VISIT OUR WEBSITE - www.showgsd.org ============================================================================