I have a 2 year old spayed bitch who suddenly stopped eating last Friday night. Saturday she wasn't interested in eating but was starting to drink volumes of water and, of course, peeing volumes of urine. I took her temp and it was 103.4 (she runs normally around 102.5), so I figured the drinking was just her attempt at self-hydration. Sunday, she was still not interestedin eating so I started giving her Ascriptin and the temp came down. On Monday, she was still not eating so I took her to the local ER. The only 'symptom' I had, in addition to the inappetance, was that she yelpedFriday morning when we played ball. The vet thought maybe it was pano (she had never had it as a young puppy, though), so she took xrays of both legs. She saw some shadowing in the carpal area of both legs which suggestedpano and the fever and inappetance seemed to go hand in hand with that diagnosis, but it didn't explain the water consumption. Tuesday she wasstill very lethargic and not eating, so I took her to my regular vet who ran a blood panel. The results came back fairly normal except for an elevated calcium level (13.5). And then I heard the words I never wanted to hear.....lymphosarcoma, multiple myeloma although, interestingly, none of herperipheral lymph nodes were enlarged. So she referred me to a 24/7 specialty clinic where an EKG was done (normal) and a chest film was taken showing no lesions. They kept her overnight, started her on IV fluids and the next morning did an ultrasound of the abdomen, liver and spleen. The ultrasound showed no enlargement of either the liver nor spleen, but massive lymph nodes in the abdomen (primarily the sublumbar area). It was beginning to look like we had a case of lymposarcoma, so they took needle aspirates of the nodes. But the cytology results came back the next day showing no sign of neoplastia/cancerous cells. Although the dog has never been out of Southern California, in looking at all possible 'rule outs', the vet wanted to check for a systemic fungal infection (blastomycosis?), so blood was drawnand has been sent to the lab to be cultured and will be back, hopfully, by next Monday/Tuesday. In the meanwhile, we are at a standstill. If anyonehas any information that could help me help the vet come to some answers, please write me. ============================================================================ POST is Copyrighted 2005. All material remains the property of the original author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind are permitted without prior permission of the original author AND of the Showgsd-l Management. ALL RIGHTS RESERVED. ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE PROSECUTED. For assistance, please contact the List Management at admin@xxxxxxxxxxxx VISIT OUR WEBSITE - http://www.showgsd.org ============================================================================