Hi Ellen, I guess I would have to moderate your statement "not breed any dog that has produced any sign of Demodex in any given litter.". All dogs carry the demodex mite and yes, it can flair up indicating an auto-immune problem..but.. there are many, many dogs that will exhibit localized spots as young dogs (sometimes due to stress) that clear up never to appear again. Are you saying that this should indicate never breeding into that line again? The situation you are dealing with is totally heartbreaking and of course breeding that animal would be wrong and I would most likely look at the parents as well and seriously question breeding them. Unless I am unaware of something, most vets consider localized and generalized demodex as almost two separate problems with two separate prognoses(sp?). A young dog with the typical spot over the eye or on the muzzle is not going to get the same treatment as the poor dog you are caring for and in most cases that I have heard of, will not develop into a generalized case unless, as you indicate there is a serious auto-immiune problem. Regards, Cynthia . Lawmanshepherds@xxxxxxx wrote: I have been caring for a P.B. rescued German Shepherd Dog for a year and a half now that had such sever Demodex that you couldn't tell this dog was a German Shepherd at first. This dog lives on oral Ivomec and Mitban dips and constant monitoring by my Vet. So far we have been able to provide him with a decent quality of life but for how long, who knows. We have flair ups all the time. Any sign of Demodex indicates an autoimmune problem. Sadly Demodex is not uncommon in our breed. Breeders need to be responsible and not breed any dog that has produced any sign of Demodex in any given litter. And remember it takes two to tango! Always breed responsibly. Our breeds reputation counts on it! Blessings to All, Ellen Stovall Blue Angel German Shepherd Dog Rescue ============================================================================ POST is Copyrighted 2006. All material remains the property of the original author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind are permitted without prior permission of the original author AND of the Showgsd-l Management. ALL RIGHTS RESERVED. ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE PROSECUTED. For assistance, please contact the List Management at admin@xxxxxxxxxxxx VISIT OUR WEBSITE - URL temporarily deleted due to AOL issues ============================================================================ --------------------------------- How low will we go? Check out Yahoo! Messenger?s low PC-to-Phone call rates. ============================================================================ POST is Copyrighted 2006. All material remains the property of the original author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind are permitted without prior permission of the original author AND of the Showgsd-l Management. ALL RIGHTS RESERVED. ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE PROSECUTED. For assistance, please contact the List Management at admin@xxxxxxxxxxxx VISIT OUR WEBSITE - URL temporarily deleted due to AOL issues ============================================================================