[ SHOWGSD-L ] Re: DM Testing

  • From: Pinehillgsds@xxxxxxx
  • To: rbuffdogs@xxxxxxxxx, diwri@xxxxxxxxxxx, showgsd-l@xxxxxxxxxxxxx
  • Date: Thu, 24 May 2012 13:17:56 -0400 (EDT)

Thank you for taking the time to post a clear and  factual explanation.
 
AND...did everyone see the form in the latest Review asking for cheek  
swabs????  So...looks like the science isn't settled after all.
 
Kathy, member GSDCA, DVGSDC
Celebrating generations  of Dual Titled TC'd Champions
visit _http://www.pinehillgsds.com/_ (http://www.pinehillgsds.com/)   

 
In a message dated 5/24/2012 12:54:31 P.M. Eastern Daylight Time,  
rbuffdogs@xxxxxxxxx writes:

Diane,
I too think it is cool they have found the allele for  this.  Great.
Problem, the GSDM specific for our breed is not being  tested for.  The GSDM
is a sensory loss disease , and it is unique to  this breed.
The DM being tested for is an ALS type DM in other breeds that  does NOT
involve
sensory loss, and does not pertain to GSDs.
Dr.  Clemmons of U of Fla was very clear on this.
It is great to have this  "tool" but if it is the wrong "tool" for your
"project" it is of very  little value.  If the "tool" has been shown to
be faulty, and comes  with a disclaimer, why does the patent holder
continue to sell  it?

We are not trying to sway anyone in any direction.  We are  trying to make
sure
people have all the known facts, all sides so they  may use that to make an
educated
decision.

In Europe , there is  NO GSD club including the SV , the worlds largest and
most powerful
club  , that just happens to pertain to our breed.. lol, endorse NO DM  test
because of inaccuracy.

Also it is estimated that 75% of German  Shepherds carry the allele.   So
you are then going to  eliminate
them from a given program?  That leaves you with only 25 %  (and with the
false clear results , probably not
even that much) to  choose from.   That is very disturbing for the breed as
it  eliminates genetic diversity
on an already too inbred, too linebred ,  breed.   Baby and bathwater.

I for one will not use the test  nor give it any weight in selection  or
de-selection of  breeding
partners until they have a test that has been studied longterm,  and
generationally for reliability of
diagnoses (which can only be done  by spinal necropsy) and prediction of
clinical outcomes.

There are  many things that mimic DM, cancer, cysts, infections, cauda
equina, injury  to discs, on
and on.   DM can only be confirmed through  necropsy.   How many necropsies
have been done
in relation to  finding an A/A "at risk" to determine reliability  and
percentage?   How come
there have been false clear  results?

To eliminate dogs from a program because of one gene out of  thousands to me
is
very dangerous for the breed.
But this is a  personal choice, based on looking at the whole thing.  Your
results  (mileage) may vary , lol
Best  regards
Kathy

*http://www.victorygermanshepherds.com*
*  <http://www.victorygermanshepherds.com/>**UPDATED: April**,  2012*
*
*
*
*
*"Victory...*Vires et honestas"



On  Thu, May 24, 2012 at 9:32 AM, Diane Wright <diwri@xxxxxxxxxxx>  wrote:

> I do not understand poo-poo'ing of DM testing. "Ohhhh...  the test MAY not
> be accurate".... "Oooooooh.... it's $65 & it's  not 100%". This mentality 
is
> rubbish... imo. Apparently I've been  watching too much BBCAmerica... as 
the
> Brits are always saying  something is  'rubbish';-)
>
>


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============================================================================
POST is Copyrighted 2011.  All material remains the property of the original 
author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind 
are permitted without prior permission of the original author AND of the 
Showgsd-l Management. ALL RIGHTS RESERVED. 

Each Author is responsible for the content of his/her post.  This group and its 
administrators are not responsible for the comments or opinions expressed in 
any post.

ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY 
MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS 
PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY 
FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE 
PROSECUTED. 

For assistance, please contact the List Management at admin@xxxxxxxxxxx

VISIT OUR WEBSITE - http://showgsd.org  
SUBSCRIPTION:http://showgsd.org/mail.html
NATIONAL BLOG - http://gsdnational.blogspot.com/
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