[ SHOWGSD-L ] Re: A Cautionary Tale
- From: genoaktortoise@xxxxxxxxxxx
- To: fhenry1@xxxxxxxxxxx, showgsd <showgsd-l@xxxxxxxxxxxxx>
- Date: Sat, 24 Nov 2007 20:35:43 +0000
Thanks for the information. That is kinda scary to me because my Nuchole has
been on metrinidazole daily for four years! She has E.P.I. and Irritated Bowel
Syndrome and when she is off her medication her stools get very soft. I always
thought Metrinidazole was a very safe medication.
Amy Greenhut
Justrock Shepherds
Leopard Tortoises
-------------- Original message --------------
From: Fran Henry <fhenry1@xxxxxxxxxxx>
> Last Monday, Luke began wobbling in the rear as he walked; his balance was
> off; he banged into things, and he didn't seem to know what his rear legs
> were doing.=20
>
> Took him to the vet Tuesday -- she thought he might be having a disk proble=
> m
> because he showed sensitivity when she palpated the spine. He's on
> cyclosporine for elevated liver enzymes, She researched side-effects to
> cyclosporine, and neurological problems were not mentioned. She did blood
> work, and his liver values are entirely normal except for the ALT, which is
> at 204 =8B normal is 12 to 118. This is the lowest it=B9s been since he got
> sic=
> k
> a year ago, so really good news on that front.
>
> We tried acupuncture Wednesday. He seemed anxious throughout.
> Then, as I was paying, I held up a treat, and he had an =B3attack=B2 of some
> sort =8B almost like a seizure. Rapid eye movements, leaning back and to one
> side =8B very scary. The vet was able to see it, which was a good thing. She
> said it looked like a vestibular problem and suggested seeing a neurologist=
> .
> She asked what drugs he was on, and I told her cyclosporine and
> metronidazole that he's been taking to counteract the diarrhea from the
> cyclosporine. She said to take him off the metronidazole. She also mentione=
> d
> an inner ear infection as a possible cause, or a tumor either inside or
> outside the brain.=20
>
> Thursday was Thanksgiving. He fell to the floor while eating in the morning=
> .
> He insisted being in whatever room I was in, but otherwise slept all day.
>
> Friday morning, Luke was MUCH better -- ate without falling down, seemed
> more sure on his feet, and had not had any more of that seizure-like
> behavior. I took him to the vet to make sure he had no inner-ear infection,
> and he didn't. He also displayed no sensitivity along the spinal column.
>
> Tentatively, she thinks he had a severe reaction to the metronidazole.
>
> When I got home, I googled Metronidazole, and found the following:
>
> "Metronidazole can cause neurologic signs if overdosed, including loss of
> balance, visual problems, vomiting, rapid eye movements (nystagmus),
> tremors and seizures. "
>
> http://www.vetinfo4dogs.com/dmetronidazole.html#Problems%20with%20Metronida=
> z
> ole%20long%20term
>
> Luke had everything but the vomiting. Luke wasn't overdosed, but he has bee=
> n
> on the drug for several weeks, The vet said, that since he was super
> sensitive to prednisone, he might just be especially drug sensitive.
>
> He's back to his old self today.
>
> I'm sending this because I've always considered metronidazole [brand name
> Flagyl] to be a very benign drug and have used it for years for occasional
> diarrhea. This whole episode has been terrifying, and I want to share the
> information in case it should happen to someone else. Luke had taken this
> drug before, but never for any prolonged period.
>
> Fran Henry
>
>
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POST is Copyrighted 2007. All material remains the property of the original
author and of GSD Communication, Inc. NO REPRODUCTIONS or FORWARDS of any kind
are permitted without prior permission of the original author AND of the
Showgsd-l Management. ALL RIGHTS RESERVED.
ALL PERSONS ARE ON NOTICE THAT THE FORWARDING, REPRODUCTION OR USE IN ANY
MANNER OF ANY MATERIAL WHICH APPEARS ON SHOWGSD-L WITHOUT THE EXPRESS
PERMISSION OF ALL PARTIES TO THE POST AND THE LIST MANAGEMENT IS EXPRESSLY
FORBIDDEN, AND IS A VIOLATION OF LAW. VIOLATORS OF THIS PROHIBITION WILL BE
PROSECUTED.
For assistance, please contact the List Management at admin@xxxxxxxxxxxx
VISIT OUR WEBSITE - www.showgsd.org
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