RMAExpress 1.0 beta 7 has been released. As usual it can be downloaded at: http://rmaexpress.bmbolstad.com Changes since 1.0 beta 6 - Improved speed ups in background correction and quantile normalization routines. This affects both RMAExpress and RMAExpressConsole. Example running RMAExpressConsole with 20 Human Exon arrays, full time for reading in all data, full RMA and wrting output to a text file on my machine (using exactly the same input/output settings): (1.0 Beta 6) 11m45.212s (1.0 Beta 7) 9m55.966s - Allow minimum of 1 array in buffer (previously could not go below 5) when selecting Preferences. This will help keep memory overhead down and is most useful for the larger arrays. - Version 4 of output settings for Console application has been introduced. This adds the ability to modify the buffer settings. - Console Application prints out more details on what was read from input/output settings files to the screen. - Add PS file support to RMADataConv. This allows the creation of CDFRME files for a pre-specified set of probesets, rather than everything specified by the PGF/CLF file. An example usage would be to create a CDFRME file that would allow you to restrict analysis and all processing to just the core exons for Human Exon arrays.