RMAExpress 1.0 beta 5 has been released. It can be downloaded at: http://rmaexpress.bmbolstad.com Changes since 1.0 beta 5 - Support for parsing PGF/CLF files in the Data Convertor application. These can be converted into CDFRME files which may be read using the main application. The goal is to properly support exon and wt gene arrays via this method. In the past these array types have been supported using CDF files. However, the CDF files for these arrays (as opposed to regular 3' expression arrays) are considered unsupported by Affymetrix, and in the future I will not make any effort to support them for RMAExpress. - CDFRME and RME files may now be read intermixed with any other format of CDF and CEL file using the "Read Unprocessed Files" option in the File menu. In the past these had to be read in using a separate option in this menu which has now been removed. Recommendations: - The 0.5 release version remains the stable version while the 1.0 beta X series are developmental releases. However, 1.0 beta 5 may be stable enough for regular use and we are near the end of this development cycle (in terms of version number, perhaps not time). Comments: - Remaining features to be implemented before 1.0 Release -- Addition of PS/MPS parsing support for the Convertor application -- Efficiency/Stability enhancments. - Please feel free to send bug reports and feature requests as needed, either to the mailing list or me directly. Only minor feature requests will be incorporated before 1.0 Release.