There several blind mainframe programmers around here. The mainframe is still a largely text based environment and poses no major hurtles for us. And NO, the mainframe is not going away any time soon. Companies are still investing Billions of dollars in hardware and software for mainframe computers. COBOL is still alive and doesn't appear to be losing much ground either. It is changing though. The mainframe is becoming more of a background processor and is being used more and more as a very large database server. I know a couple of blind people in the area where I live that came into programming through mainframe and have moved up into management. I know of at least one guy who is a DASD manager for a large mainframe shop and another who is an operating system controller for a large state university. I'd believe almost any job on the mainframe or AS-400 is easily accessible. I myself have been doing it for 22 years and I know others on this list are also employed in this kind of work.