Ethan Um Um Good and just think this only an afternoon snack :-) Bill >>> Ethan Priel <prieleye@xxxxxxxxxxxxxxxx> 7/9/2010 3:24 PM >>> Paula, Good luck getting an answer out of Bill for the next few hours. By accident, his email program sent me a copy of his take-out order (encl.) which was just delivered. Ethan ********************************************* Order #: 3495 Date: July 8 2010 Deliver to: Anderson,Bill 5323 Harry Hines Blvd Delivery time: Immediate (big tip offered!) 2 bags chips 2 quarts chocolate ice cream 1 jar cherries 1 bag pistachios 1 fruit cup 3 orange slushies 1 chocolate chip cookie 1(addtl.) chocolate chip cookie 1 serving pickle 1 pizza – olives, tuna, mayo, carrots 1 small milk -----Original Message----- From: optimal-bounce@xxxxxxxxxxxxx [mailto:optimal-bounce@xxxxxxxxxxxxx] On Behalf Of Paula Morris Sent: 09 July, 2010 23:04 To: 'optimal@xxxxxxxxxxxxx' Subject: [optimal] Re: Vegetable Dye Bill, Are you telling me that the glowing armadillos of West Texas/ East New Mexico are the result of fluoreo tree snacking and NOT Los Alamos?? Or, could Ethan be correct? ;-) -----Original Message----- From: optimal-bounce@xxxxxxxxxxxxx [mailto:optimal-bounce@xxxxxxxxxxxxx] On Behalf Of William Anderson Sent: Friday, July 09, 2010 1:51 PM To: 'optimal@xxxxxxxxxxxxx' Subject: [optimal] Re: Vegetable Dye Paula WHAT, I thought it came from the Fluoreo tree that grows out in West Texas and in the mountains in Utah. I heard the way it was discovered was when the Glow Injuns were hunting Jacklopes at night under a blue moon after the Jacklopes had eaten berries off of the Fluoreo tree all day Bill >>> Paula Morris <paula.morris@xxxxxxxxxxxx> 7/9/2010 2:07 PM >>> Hey Sarah, The rumor exists because it was stated to be a vegetable dye extracted from a plant resin first by Duke-Elder, and then by J Federman in the Intravenous Fluorescein Angiography chapter in Duane's Clinical Ophthalmology, 1991. That has since been corrected in more recent editions of Duane's. Fluorescein's basic component is naphthalene (an extract from the carbolic acid fraction of coal tar). It is heated with mercury sulfate and copper sulfate to 400-500 degrees Celsius to become phthallic anhydride. It is then heated with resorcinol to 200 degrees C. to become resorcinolphthalein, or fluorescein, which is highly insoluble. When resorcinolphthalein is dissolved in sodium hydroxide solution, it becomes fluorescein sodium which is highly soluble and what we use in retinal angiography. Why do I know this? Because our own Joe Warnicki challenged me back in 1990 to research "Where Does Fluorescein Come From?" That quest led me to research HJ Conn's biological Stains, the Merck index: An Encyclopedia of Chemicals, Drugs and Biologicals, Remington's Pharmaceutical Sciences, and Drug Facts and Comparisons. Fluorescein Sodium is a synthetic dye assigned by the government to be called F,(food), D (drugs), & C(cosmetics) color yellow #8. The F,D,C colors are only given to synthetic dyes. So - it has a vegetable base if you want to harken back to pre-historic history as plants contributed to the formation of coal deposits, but more recently I think you could safely say it has a mineral source - naphthalene, ths tuff that makes moth balls stink. Probably don't want to tell you patients that............... And Thus endeth the chemistry lesson! p From: optimal-bounce@xxxxxxxxxxxxx [mailto:optimal-bounce@xxxxxxxxxxxxx] On Behalf Of Sarah Moyer Sent: Friday, July 09, 2010 10:06 AM To: optimal@xxxxxxxxxxxxx Subject: [optimal] Vegetable Dye July is here and so are the new residents! During a lect ure/discussion about fluorescein sodium yesterday, we discussed how fluorescein sodium is a synthetic dye and NOT a vegetable dye. One of them had already read/heard it was a vegetable dye. He asked if there were ever ingredients in the dye that were vegetable based and if that is why this rumor exists. Does anybody know why some people refer to it as a vegetable dye? Thanks! Sarah Moyer University of North Carolina