<!-- @page { margin: 2cm } P { margin-bottom: 0.21cm } --> Dear all, thanks for all the responses! So, basically it seems that except from tweaking my assembly by lowering the coverage and fixing -CO:mrpg (which I'm working on right now) there is only one way: get dirty with finishing. However, this leads to a more general question: what do you guys think of draft genomes? I see more and more papers that ditch finishing completely and simply analyze the contigs they obtain with basic assemblies (newbler, velvet...). Do you guys believe those data to be sound enough? Of course it depends on the analyses that are to be done, but some thoughts from the experts (that would be you) could be very insightful. D.